CAS 76128-71-7

4-Chloro-2-(4-fluorophenyl)pyrimidine

Description:

4-Chloro-2-(4-fluorophenyl)pyrimidine is a heterocyclic organic compound characterized by its pyrimidine ring, which is a six-membered aromatic ring containing two nitrogen atoms at positions 1 and 3. The compound features a chloro substituent at the 4-position and a 4-fluorophenyl group at the 2-position of the pyrimidine ring. This structure contributes to its potential biological activity and makes it of interest in medicinal chemistry. The presence of halogen atoms, such as chlorine and fluorine, often enhances the lipophilicity and metabolic stability of the compound, which can influence its pharmacological properties. 4-Chloro-2-(4-fluorophenyl)pyrimidine may exhibit various chemical reactivity patterns typical of pyrimidine derivatives, including nucleophilic substitution and electrophilic aromatic substitution. It is important to handle this compound with care, following appropriate safety protocols, as with many chemical substances, due to potential toxicity and environmental impact. Its applications may span across pharmaceuticals, agrochemicals, and materials science, depending on its specific properties and reactivity.

Formula: C₁₀H₆ClFN₂

InChI: InChI=1S/C10H6ClFN2/c11-9-5-6-13-10(14-9)7-1-3-8(12)4-2-7/h1-6H

InChI key: InChIKey=UPHJPEPWOCWYDB-UHFFFAOYSA-N

SMILES: ClC1=NC(=NC=C1)C2=CC=C(F)C=C2

Synonyms:

• Pyrimidine, 4-chloro-2-(4-fluorophenyl)-
• 4-Chloro-2-(4-fluorophenyl)pyrimidine