CAS 76134-77-5

Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-, hydrochloride (1:1)

Description:

Dibenzo[c,f]pyrazino[1,2-a]azepine, 1,2,3,4,10,14b-hexahydro-, hydrochloride (1:1), with CAS number 76134-77-5, is a chemical compound characterized by its complex polycyclic structure, which includes fused benzene and azepine rings. This compound typically exhibits properties associated with heterocyclic compounds, including potential pharmacological activity due to its unique molecular configuration. The hydrochloride salt form indicates that it is a hydrochloride, which often enhances solubility in water and stability. Such compounds are of interest in medicinal chemistry, particularly for their potential applications in treating various neurological or psychiatric disorders. The hexahydro designation suggests that the compound is saturated, which may influence its reactivity and biological interactions. As with many heterocycles, the presence of nitrogen atoms in the ring structure can contribute to its basicity and ability to form hydrogen bonds, impacting its interaction with biological targets. Overall, this compound represents a class of substances that may have significant therapeutic potential, warranting further investigation into its biological properties and mechanisms of action.

Formula: C₁₇H₁₈N₂.ClH

InChI: InChI=1S/C17H18N2.ClH/c1-3-7-15-13(5-1)11-14-6-2-4-8-16(14)19-10-9-18-12-17(15)19;/h1-8,17-18H,9-12H2;1H

InChI key: InChIKey=KVJGBZBVKLKGRN-UHFFFAOYSA-N

SMILES: C12N(C=3C(CC=4C1=CC=CC4)=CC=CC3)CCNC2.Cl

Normianserin Hydrochloride 1.0 mg/ml in Methanol (as free base)

CAS: 76134-77-5

Color and Shape: Single Solution

Ref: 61-AMP0147.05-01

Mianserin EP Impurity E HCl

CAS: 76134-77-5

Formula: C₁₇H₁₈N₂·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 250.35 36.46

Ref: 4Z-M-091

Mianserin EP Impurity E-d4 HCl

CAS: 76134-77-5

Formula: C₁₇H₁₄D₄N₂·HCl

Molecular weight: 254.37 36.46

Ref: 4Z-M-0912

(14bRS)-1,2,3,4,10,14b-Hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine Hydrochloride (Desmethylmianserin Hydrochloride)

Controlled Product

CAS: 76134-77-5

Formula: C₁₇H₁₈N₂·ClH

Color and Shape: Neat

Molecular weight: 286.80

Ref: 86-MM0147.05

Nor Mianserin Hydrochloride

Controlled Product

CAS: 76134-77-5

Applications Nor Mianserin Hydrochloride is the active metabolite of Miansein Hydrochloride (M341500), an antidepressant and a serotonin receptor antagonist.
References Kent, J., et al.: Lancet, 355, 911 (2000); Maurer, H., et al.: Ther. Drug Monit., 24, 117 (2002); Saxena, et al.: Eur. J. Pharmacol., 13, 295 (1971); Brogden, R.N., et al.: Drugs, 16, 273 (1978); Alexander, B.S., et al.: J. Pharm. Pharmacol., 39, 664 (1987)

Formula: C₁₇H₁₈N₂·ClH

Color and Shape: White To Light Yellow

Molecular weight: 286.80

Ref: TR-N736807