CAS 761423-87-4

Ipragliflozin

Description:

Ipragliflozin is a medication primarily used in the management of type 2 diabetes mellitus. It belongs to the class of drugs known as sodium-glucose co-transporter 2 (SGLT2) inhibitors, which work by preventing the reabsorption of glucose in the kidneys, thereby promoting its excretion in urine and lowering blood glucose levels. The chemical formula of Ipragliflozin is C17H21O5S, and it features a sulfonyl group, which is integral to its mechanism of action. Ipragliflozin is characterized by its ability to improve glycemic control, promote weight loss, and potentially provide cardiovascular benefits. It is typically administered orally and is often prescribed in conjunction with other antidiabetic agents. Common side effects may include urinary tract infections and dehydration due to increased urination. As with any medication, it is essential for patients to consult healthcare professionals for personalized advice and monitoring while using Ipragliflozin.

Formula: C₂₁H₂₁FO₅S

InChI: InChI=1S/C21H21FO5S/c22-15-6-5-12(21-20(26)19(25)18(24)16(10-23)27-21)7-13(15)9-14-8-11-3-1-2-4-17(11)28-14/h1-8,16,18-21,23-26H,9-10H2/t16-,18-,19+,20-,21+/m1/s1

InChI key: InChIKey=AHFWIQIYAXSLBA-RQXATKFSSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC3=CC=4C(S3)=CC=CC4)=C(F)C=C2

Synonyms:

• (1S)-1,5-Anhydro-1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-<span class="text-smallcaps">D</span>-glucitol
• (1S)-1,5-Anhydro-1-C-[3-[(1-benzothiophen-2-yl)methyl]-4-fluorophenyl]-D-glucitol
• <span class="text-smallcaps">D</span>-Glucitol, 1,5-anhydro-1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-, (1S)-
• Asp 1941
• Suglat
• D-Glucitol, 1,5-anhydro-1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-, (1S)-
• (1S)-1,5-Anhydro-1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-D-glucitol
• Ipragliflozin
• Ipragliflozin, >=98%
• Ipragliflozin, (1S)-1,5-Anhydro-1-C-[3-[(1-benzothiophen-2-yl)Methyl]-4-fluorophenyl]-D-glucitol
• IpragliflozinL-Proline
• IpragliflozinL-Proline int
• Ipragliflozin impuity
• Ipragliflozin Impurity
• ASP-1941/D-Glucitol, 1,5-anhydro-1-C-[3-(benzo[b]thien-2-ylMethyl)-4-fluorophenyl]-, (1S)-
• Ipragliflozin (ASP1941)
• Ipragliflozin-002
• CS-1580
• Ipragliflozin （Suglat）

D-Glucitol,1,5-anhydro-1-C-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-, (1S)-

CAS: 761423-87-4

Formula: C₂₁H₂₁FO₅S

Purity: 98%

Color and Shape: Solid

Molecular weight: 404.4518

Ref: IN-DA00ICPF

Ipragliflozin

CAS: 761423-87-4

Formula: C₂₁H₂₁FO₅S

Color and Shape: Off-White Solid

Molecular weight: 404.45

Ref: 4Z-I-074001

Ipragliflozin-13C6

CAS: 761423-87-4

Formula: C₁₅₁₃C₆H₂₁FO₅S

Color and Shape: White To Off-White Solid

Molecular weight: 410.41

Ref: 4Z-I-074006

(2S,3R,4R,5S,6R)-2-(3-(Benzo[B]Thiophen-2-Ylmethyl)-4-Fluorophenyl)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol

CAS: 761423-87-4

(2S,3R,4R,5S,6R)-2-(3-(Benzo[B]Thiophen-2-Ylmethyl)-4-Fluorophenyl)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol

Purity: 98%

Molecular weight: 404.45g/mol

Ref: 54-PC109063

Ipragliflozin

CAS: 761423-87-4

Ipragliflozin

Purity: ≥98%

Molecular weight: 404.45g/mol

Ref: 54-BUP15797

Ipragliflozin

CAS: 761423-87-4

Color and Shape: Neat

Ref: 86-MM3943.00

Ipragliflozin

CAS: 761423-87-4

Formula: C₂₁H₂₁FO₅S

Purity: >95.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 404.45

Ref: 3B-I1284

Ipragliflozin-d3

CAS: 761423-87-4

Formula: C₂₁H₁₈D₃FO₅S

Molecular weight: 407.47

Ref: 4Z-I-074004

Ipragliflozin

CAS: 761423-87-4

Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.

Formula: C₂₁H₂₁FO₅S

Purity: 99.38% - 99.70%

Color and Shape: Solid

Molecular weight: 404.45

Ref: TM-T2385

Ipragliflozin-d5

CAS: 761423-87-4

Formula: C₂₁H₁₆D₅FO₅S

Molecular weight: 409.48

Ref: 4Z-I-074005

Ipragliflozin

Controlled Product

CAS: 761423-87-4

Applications Ipragliflozin is a potent and selective inhibitor of sodium-glucose cotransporter-2 (SGLT2) and can serve as a potential agent for the treatment of type 1 and type 2 diabetes.
References Kadokura, T., et al.: Clin. Pharmacokinet., 53, 975 (2014); Kashiwagi, A., et al.: J. Diabetes Investig., 5, 382 (2014); Tahara, A., et al.: J. Pharm. Pharmacol., 66, 975 (2014); Zhang, W., et al.: Clin. Drug Invest., 33, 489 (2013)

Formula: C₂₁H₂₁FO₅S

Color and Shape: White

Molecular weight: 404.45

Ref: TR-I739475

Ipragliflozin

CAS: 761423-87-4

Inhibitor of sodium-glucose cotransporter SGLT2

Formula: C₂₁H₂₁FO₅S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 404.45 g/mol

Ref: 3D-FA58137