CAS: 761439-42-3 - 5-chloro-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}-N~4~-[2-(propan-2-ylsulfonyl)phenyl]pyrimidine-2,4-diamine

Formula: C₃₀H₄₀ClN₇O₃S

InChI: InChI=1S/C30H40ClN7O3S/c1-21(2)42(39,40)28-8-6-5-7-26(28)33-29-24(31)20-32-30(35-29)34-25-10-9-23(19-27(25)41-4)37-13-11-22(12-14-37)38-17-15-36(3)16-18-38/h5-10,19-22H,11-18H2,1-4H3,(H2,32,33,34,35)

InChI key: InChIKey=QQWUGDVOUVUTOY-UHFFFAOYSA-N

SMILES: O=S(=O)(C=1C=CC=CC1NC2=NC(=NC=C2Cl)NC3=CC=C(C=C3OC)N4CCC(N5CCN(C)CC5)CC4)C(C)C

Synonyms:

• 2,4-Pyrimidinediamine, 5-chloro-N²-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N⁴-[2-[(1-methylethyl)sulfonyl]phenyl]-
• 5-Chloro-N²-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N⁴-[2-[(1-methylethyl)sulfonyl]phenyl]-2,4-pyrimidinediamine
• Ae 684
• Nvp-Tae 684
• Nvp-Tae684-Tae 684
• Nvt Tae-684
• Tae 684
• Tae684(Nvp-Tae684)

TAE684 (NVP-TAE684)

CAS: 761439-42-3

• Formula: C₃₀H₄₀ClN₇O₃S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 614.2017

TAE684

CAS: 761439-42-3

NVP-TAE 684

CAS: 761439-42-3

NVP-TAE 684 (TAE684) is a excellently effective and specific ALK inhibitor(IC50=3 nM).

• Formula: C₃₀H₄₀ClN₇O₃S
• Purity: 99.91%
• Color and Shape: Solid
• Molecular weight: 614.2

NVP-TAE684

CAS: 761439-42-3

Inhibitor of NPM-ALK kinase

• Formula: C₃₀H₄₀ClN₇O₃S
• Purity: Min. 95%
• Molecular weight: 614.2 g/mol

TAE 684

CAS: 761439-42-3

Applications TAE 684 is a potent, selective, and efficacious inhibitor of NPM-ALK, a fusion protein …

• Formula: C₃₀H₄₀ClN₇O₃S
• Color and Shape: White to Pale Yellow Solid
• Molecular weight: 614.20