CAS 762-42-5

Dimethyl acetylenedicarboxylate

Description:

Dimethyl acetylenedicarboxylate (DMAD) is an organic compound characterized by its structure, which features two carboxylate groups attached to a central acetylenic carbon framework. It is a colorless to pale yellow liquid with a distinctive fruity odor. DMAD is known for its reactivity, particularly in Diels-Alder reactions and as a Michael acceptor, making it valuable in organic synthesis for constructing complex molecules. The compound is soluble in organic solvents such as ethanol and ether but has limited solubility in water. It is also recognized for its potential toxicity and should be handled with care, as it can cause irritation to the skin, eyes, and respiratory system. In terms of stability, DMAD is relatively stable under normal conditions but can undergo polymerization or decomposition when exposed to heat or light. Its applications extend to the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals, highlighting its significance in the field of organic chemistry.

Formula: C₆H₆O₄

InChI: InChI=1S/C6H6O4/c1-9-5(7)3-4-6(8)10-2/h1-2H3

InChI key: InChIKey=VHILMKFSCRWWIJ-UHFFFAOYSA-N

SMILES: C(C#CC(OC)=O)(OC)=O

Synonyms:

• 1,2-Bis(methoxycarbonyl)acetylene
• 1,2-Bis(methoxycarbonyl)ethyne
• 1,4-Dimethyl but-2-ynedioate
• 2-Butynedioic acid dimethyl ester
• 2-Butynedioic acid, 1,4-dimethyl ester
• Acetylendicarbonsaeure-Dimethylester
• Acetylenedicarboxylic acid dimethyl ester
• Bis(carbomethoxy)acetylene
• Bis(methoxycarbonyl)acetylene
• But-2-Ynedioate, Dimethyl
• Butinodioato De Dimetilo
• Butynedioate de dimethyle
• Butynedioic acid dimethyl ester
• Di(carbomethoxy)acetylene
• Dimethyl 1,2-acetylenedicarboxylate
• Dimethyl 2-butynedioate
• Dimethyl But-2-Ynedioate
• Dimethyl Butynedioate
• Dimethyl acetylenedicarboxylate (DMADC)
• Dimethyl butyne-1,4-dioate
• Dimethyl ethynedicarboxylate
• Dimethylaceylene dicarboxylate
• Dimethylbutindioat
• Dmad
• Nsc 101119
• Nsc 14912

Dimethyl Acetylenedicarboxylate

CAS: 762-42-5

Formula: C₆H₆O₄

Purity: >96.0%(GC)

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 142.11

Ref: 3B-A0090

Dimethyl acetylenedicarboxylate, 98%

CAS: 762-42-5

It acts as an inhibitor of oxidative phosphorylation. It is also used in Pharmaceutical and electronic industry. It is used in organic synthesis. It also acts as an intermediate in chemical research. It is also used in Diels-Alder Reaction. This Thermo Scientific Chemicals brand product was origi

Formula: C₆H₆O₄

Purity: 98%

Color and Shape: Liquid, Clear colorless to yellow

Molecular weight: 142.11

Ref: 02-A11437

Dimethyl acetylenedicarboxylate, 95%

CAS: 762-42-5

Dimethyl acetylenedicarboxylate as a versatile dienophile used in Diels-Alder reactions. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / i

Formula: C₆H₆O₄

Purity: 95%

Color and Shape: Colorless to pale yellow, Liquid

Molecular weight: 142.11

Ref: 02-045131

dimethyl but-2-ynedioate

CAS: 762-42-5

Formula: C₆H₆O₄

Purity: 95%

Color and Shape: Liquid

Molecular weight: 142.1094

Ref: IN-DA0034R0

Dimethyl but-2-yne-1,4-dioate

CAS: 762-42-5

Dimethyl but-2-yne-1,4-dioate

Formula: C₆H₆O₄

Purity: 98%

Color and Shape: clear. light yellow liquid

Molecular weight: 142.11g/mol

Ref: 54-OR1955

Dimethyl acetylenedicarboxylate

CAS: 762-42-5

Formula: CH₃O₂CCCCO₂CH₃

Purity: ≥ 97.5%

Color and Shape: Clear, colourless to yeloow or pale yellow-green liquid

Molecular weight: 142.11

Ref: 7W-GK1507

Dimethyl acetylenedicarboxylate

CAS: 762-42-5

Purity: 98.0%

Color and Shape: Liquid, Clear

Molecular weight: 142.11000061035156

Ref: 10-F049730

Dimethyl acetylene dicarboxylate

CAS: 762-42-5

Dimethyl acetylene dicarboxylate (DMAD) is an anti-infective agent that targets the pyrrole system in enzymes. It inhibits the synthesis of bacterial proteins and has been shown to have antiviral activity against HIV. DMAD binds to a specific site on the enzyme and prevents it from functioning normally. This causes a decrease in the production of proteins needed for cell division and can lead to cell death. DMAD also has been shown to inhibit the growth of bacteria by binding to receptor sites, preventing protein synthesis, and altering enzyme activity. X-ray diffraction data and x-ray crystal structures reveal that DMAD is a stable compound which forms stable complexes with metal ions. These complexes are formed through hydrogen bonding interactions with amino acid residues in the active site of enzymes.

Formula: C₆H₆O₄

Purity: Min. 95%

Molecular weight: 142.1 g/mol

Ref: 3D-FD10835

Dimethyl Acetylenedicarboxylate

Controlled Product

CAS: 762-42-5

Applications Dimethyl Acetylenedicarboxylate is a biocide that is added to biodiesels to inhibit and remove microbial growth. It can rapidly penetrate the skin and cause aberrations in the activities of the glycogenic, lipogenic, and tricarboxylic acid metabollic pathways. It also causes delayed and pain-free dermal burns.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Poon, R., et al.: Arch. Toxicol., 85(11), 1419-1427 (2011); Klain, George J., et al.: Fund. Appl. Toxicol., 10(4), 730-5 (1988); Slovak, A. J. M., et al.: Contact Dermatitis, 11(1), 29-30 (1984)

Formula: C₆H₆O₄

Color and Shape: Neat

Molecular weight: 142.11

Ref: TR-D461530