CAS 76204-02-9
:4-methylumbelliferyl-N-acetyl-alpha-D-neuram.A.so-S.dihy.
Description:
4-Methylumbelliferyl-N-acetyl-alpha-D-neuraminate, commonly referred to as 4-MU-NANA, is a synthetic substrate used primarily in biochemical assays to detect neuraminidase activity. This compound features a 4-methylumbelliferone moiety, which is a fluorescent marker, allowing for sensitive detection when the substrate is hydrolyzed by neuraminidase enzymes. The presence of the N-acetyl-alpha-D-neuraminate structure makes it a specific substrate for enzymes that cleave sialic acid residues. Upon enzymatic action, the release of 4-methylumbelliferone results in a measurable increase in fluorescence, facilitating quantitative analysis. This compound is particularly valuable in virology and microbiology for studying pathogens that express neuraminidase, such as influenza viruses. Additionally, its stability and solubility in aqueous solutions make it suitable for various laboratory applications. Overall, 4-MU-NANA serves as an important tool in research and diagnostic settings, contributing to our understanding of sialic acid metabolism and enzyme kinetics.
Formula:C21H24NNaO11
InChI:InChI=1/C21H25NO11.Na/c1-9-5-16(27)31-15-6-11(3-4-12(9)15)32-21(20(29)30)7-13(25)17(22-10(2)24)19(33-21)18(28)14(26)8-23;/h3-6,13-14,17-19,23,25-26,28H,7-8H2,1-2H3,(H,22,24)(H,29,30);/q;+1/p-1/t13?,14-,17?,18-,19?,21?;/m1./s1
SMILES:Cc1cc(=O)oc2cc(ccc12)OC1(CC(C(C(C(C(CO)O)O)O1)N=C(C)O)O)C(=O)O.[Na]
Synonyms:- 2-(4-Methylumbelliferyl)-a-D-N-acetylneuraminic acid, sodium salt
- 2-(4-methylumbelliferyl)-A-D-N-*acetylneuraminic
- 2'-(4-Methylumbelliferyl)-Alpha-D-N-Acetylneuraminic Acid Sodium Salt
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Found 8 products.
4-Methylumbelliferyl-N-acetyl-α-D-neuraminic Acid Sodium Salt
CAS:Formula:C21H24NNaO11Purity:>93.0%(HPLC)Color and Shape:White to Light yellow powder to crystalMolecular weight:489.414-MUNANA
CAS:<p>4-MUNANA (4-Methylumbelliferyl-N-acetyl-α-D-Neuraminic Acid sodium salt) is a fluorescent substrate and substrate analogue for neuraminidase activity assays.</p>Formula:C21H24NNaO11Purity:98.02%Color and Shape:SolidMolecular weight:489.412'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate
CAS:<p>2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate</p>Color and Shape:Pale Yellow PowderMolecular weight:507.42g/mol2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic Acid, Sodium Salt
CAS:Controlled ProductFormula:C21H24NO11·NaColor and Shape:NeatMolecular weight:489.412'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid, sodium salt
CAS:<p>4-Methylumbelliferyl N-acetyl-a-D-neuraminic acid sodium salt (4-MUNANA) is a fluorogenic substrate of neuraminidase. 4-Methylumbelliferone is released from 4-MUNANA by neuraminidase in the assay and can be detected fluorometrically with excitation at 365-380 nm and emission at 445-454 nm. It can also be used for fluorescent staining of sialidases in PAGE.</p>Formula:C21H24NNaO11Purity:Min. 98 Area-%Molecular weight:489.42 g/mol2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid, sodium salt
CAS:<p>2'-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid, sodium salt is a fluorogenic substrate for alpha-galactosidase. It is used in the analysis of cultured media and as a conjugate for enzyme substrates. This product has been shown to be useful in food testing, diagnostics, and environmental testing. 2'-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid, sodium salt has been used as a chromogenic substrate for the detection of alpha-galactosidase activity. This product is also used as a bioluminescent substrate for the detection of bioluminescence.</p>Formula:C21H24NNaO11Purity:Min. 96.5 Area-%Molecular weight:489.42 g/mol
