CAS 76204-02-9

4-methylumbelliferyl-N-acetyl-alpha-D-neuram.A.so-S.dihy.

Description:

4-Methylumbelliferyl-N-acetyl-alpha-D-neuraminate, commonly referred to as 4-MU-NANA, is a synthetic substrate used primarily in biochemical assays to detect neuraminidase activity. This compound features a 4-methylumbelliferone moiety, which is a fluorescent marker, allowing for sensitive detection when the substrate is hydrolyzed by neuraminidase enzymes. The presence of the N-acetyl-alpha-D-neuraminate structure makes it a specific substrate for enzymes that cleave sialic acid residues. Upon enzymatic action, the release of 4-methylumbelliferone results in a measurable increase in fluorescence, facilitating quantitative analysis. This compound is particularly valuable in virology and microbiology for studying pathogens that express neuraminidase, such as influenza viruses. Additionally, its stability and solubility in aqueous solutions make it suitable for various laboratory applications. Overall, 4-MU-NANA serves as an important tool in research and diagnostic settings, contributing to our understanding of sialic acid metabolism and enzyme kinetics.

Formula: C₂₁H₂₄NNaO₁₁

InChI: InChI=1/C21H25NO11.Na/c1-9-5-16(27)31-15-6-11(3-4-12(9)15)32-21(20(29)30)7-13(25)17(22-10(2)24)19(33-21)18(28)14(26)8-23;/h3-6,13-14,17-19,23,25-26,28H,7-8H2,1-2H3,(H,22,24)(H,29,30);/q;+1/p-1/t13?,14-,17?,18-,19?,21?;/m1./s1

SMILES: Cc1cc(=O)oc2cc(ccc12)OC1(CC(C(C(C(C(CO)O)O)O1)N=C(C)O)O)C(=O)O.[Na]

Synonyms:

• 2-(4-Methylumbelliferyl)-a-D-N-acetylneuraminic acid, sodium salt
• 2-(4-methylumbelliferyl)-A-D-N-*acetylneuraminic
• 2'-(4-Methylumbelliferyl)-Alpha-D-N-Acetylneuraminic Acid Sodium Salt

4-Methylumbelliferyl-N-acetyl-α-D-neuraminic Acid Sodium Salt

CAS: 76204-02-9

Formula: C₂₁H₂₄NNaO₁₁

Purity: >93.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 489.41

Ref: 3B-M3031

Neu5Ac-α-4MU

CAS: 76204-02-9

Formula: C₂₁H₂₄NNaO₁₁

Purity: 95%

Color and Shape: Solid

Molecular weight: 489.4051

Ref: IN-DA00577M

4-MUNANA

CAS: 76204-02-9

4-MUNANA (4-Methylumbelliferyl-N-acetyl-α-D-Neuraminic Acid sodium salt) is a fluorescent substrate and substrate analogue for neuraminidase activity assays.

Formula: C₂₁H₂₄NNaO₁₁

Purity: 98.02%

Color and Shape: Solid

Molecular weight: 489.41

Ref: TM-T38120

Neu5Ac-α-4MU

CAS: 76204-02-9

Molecular weight: 489.39

Ref: 7W-GC1361

2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate

CAS: 76204-02-9

2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate

Color and Shape: Pale Yellow Powder

Molecular weight: 507.42g/mol

Ref: 54-BIB6114

2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic Acid, Sodium Salt

Controlled Product

CAS: 76204-02-9

Formula: C₂₁H₂₄NO₁₁·Na

Color and Shape: Neat

Molecular weight: 489.41

Ref: TR-M334200

2'-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid, sodium salt

CAS: 76204-02-9

4-Methylumbelliferyl N-acetyl-a-D-neuraminic acid sodium salt (4-MUNANA) is a fluorogenic substrate of neuraminidase. 4-Methylumbelliferone is released from 4-MUNANA by neuraminidase in the assay and can be detected fluorometrically with excitation at 365-380 nm and emission at 445-454 nm. It can also be used for fluorescent staining of sialidases in PAGE.

Formula: C₂₁H₂₄NNaO₁₁

Purity: Min. 98 Area-%

Molecular weight: 489.42 g/mol

Ref: 3D-M-5507

2'-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid, sodium salt

CAS: 76204-02-9

2'-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid, sodium salt is a fluorogenic substrate for alpha-galactosidase. It is used in the analysis of cultured media and as a conjugate for enzyme substrates. This product has been shown to be useful in food testing, diagnostics, and environmental testing. 2'-(4-Methylumbelliferyl)-alpha-D-N-acetylneuraminic acid, sodium salt has been used as a chromogenic substrate for the detection of alpha-galactosidase activity. This product is also used as a bioluminescent substrate for the detection of bioluminescence.

Formula: C₂₁H₂₄NNaO₁₁

Purity: Min. 96.5 Area-%

Molecular weight: 489.42 g/mol

Ref: 3D-M-5508