CAS 762240-92-6: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

Description: 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride is a chemical compound characterized by its unique bicyclic structure, which incorporates both triazole and pyrazine moieties. The presence of a trifluoromethyl group enhances its lipophilicity and may influence its biological activity. This compound is typically encountered as a hydrochloride salt, which improves its solubility in aqueous environments, making it suitable for various applications, including pharmaceutical research. The tetrahydro configuration indicates that the compound is saturated, contributing to its stability and potentially affecting its reactivity. Its molecular structure suggests potential interactions with biological targets, making it of interest in medicinal chemistry. The compound's CAS number, 762240-92-6, allows for precise identification and retrieval of information in chemical databases. Overall, this substance exemplifies the complexity and diversity of heterocyclic compounds, with implications for drug development and other chemical applications.

Formula: C₆H₇F₃N₄·ClH

InChI: InChI=1S/C6H7F3N4.ClH/c7-6(8,9)5-12-11-4-3-10-1-2-13(4)5;/h10H,1-3H2;1H

InChI key: InChIKey=AQCSCRYRCRORET-UHFFFAOYSA-N

SMILES: Cl.FC(F)(F)C1=NN=C2N1CCNC2

Synonyms:

• 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1)
• 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, monohydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-Retrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine Hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-1,2,4-Triazolo-[4,3-Alpha] Pyrazine Hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-[1,2,4]Traazoli[4,3-1]Pyrazine Hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro[1,2,4]Triazolo[4,3-A]Pyrazine
• 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro[1,2,4]Triazolo[4,3-A]Pyrazine Hydrochloride (1:1)
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-(1,2,4)trazolo(4,3-a)pyrazine hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hcl
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine monohydrochloride
• 3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
• IntermediateⅠof Sitagliptin phosphate
• Sitagliptin Intermediate
• Tap-4

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride

CAS: 762240-92-6

• Formula: C₆H₇F₃N₄·HCl
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 228.60

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine hydrochloride, 98+%

CAS: 762240-92-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. …

• Formula: C₆H₈ClF₃N₄
• Purity: 98+%
• Molecular weight: 228.60

3-Trifluoromethyl-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyrazine hydrochloride

CAS: 762240-92-6

• Purity: 98.0%
• Color and Shape: Solid
• Molecular weight: 228.60000610351562

3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-[1,2,4]Triazolo[4,3-a]Pyrazine Hydrochloride

CAS: 762240-92-6

• Formula: C₆H₈ClF₃N₄
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 228.6027

Sitagliptin Intermediate 2

CAS: 762240-92-6

• Purity: ≥98%
• Molecular weight: 228.603g/mol

Sitagliptin Impurity 20 HCl

CAS: 762240-92-6

• Formula: C₆H₇F₃N₄·HCl
• Color and Shape: White To Off-White Solid
• Molecular weight: 192.15 36.46

Sitagliptin Intermediate 2

CAS: 762240-92-6

Sitagliptin Intermediate 2 is a useful organic compound that has been used in life science …

• Formula: C₆H₈ClF₃N₄
• Purity: 98%
• Color and Shape: Yellow-Brown Solid Crystalline
• Molecular weight: 228.603

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride

CAS: 762240-92-6

• Formula: C₆H₇F₃N₄·ClH
• Color and Shape: Neat
• Molecular weight: 228.60

5,6,7,8-Tetrahydro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

CAS: 762240-92-6

• Formula: C₆H₇F₃N₄·ClH
• Purity: 98%
• Color and Shape: white to off-white solid
• Molecular weight: 228.60g/mol

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-d4 Hydrochloride

CAS: 762240-92-6

Applications Isotope labelled Sitagliptin (S491000) intermediate. References Mohri, K., et al.: Chem. Pharm. Bull., 30, …

• Formula: C₆H₃D₄F₃N₄·x(HCl)
• Color and Shape: Neat
• Molecular weight: 196.17 + x(36.46)

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride

CAS: 762240-92-6

Applications Sitagliptin intermediate. References Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982), Sarges, …

• Formula: C₆H₇F₃N₄·ClH
• Color and Shape: White
• Molecular weight: 228.60

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

CAS: 762240-92-6

Inhibitor of DDP-4 peptidase

• Formula: C₆H₇F₃N₄•HCl
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 228.6 g/mol