CAS 762240-92-6

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

Description:

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride is a chemical compound characterized by its unique bicyclic structure, which incorporates both triazole and pyrazine moieties. The presence of a trifluoromethyl group enhances its lipophilicity and may influence its biological activity. This compound is typically encountered as a hydrochloride salt, which improves its solubility in aqueous environments, making it suitable for various applications, including pharmaceutical research. The tetrahydro configuration indicates that the compound is saturated, contributing to its stability and potentially affecting its reactivity. Its molecular structure suggests potential interactions with biological targets, making it of interest in medicinal chemistry. The compound's CAS number, 762240-92-6, allows for precise identification and retrieval of information in chemical databases. Overall, this substance exemplifies the complexity and diversity of heterocyclic compounds, with implications for drug development and other chemical applications.

Formula: C₆H₇F₃N₄·ClH

InChI: InChI=1S/C6H7F3N4.ClH/c7-6(8,9)5-12-11-4-3-10-1-2-13(4)5;/h10H,1-3H2;1H

InChI key: InChIKey=AQCSCRYRCRORET-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C=1N2C(=NN1)CNCC2.Cl

Synonyms:

• 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, hydrochloride (1:1)
• 1,2,4-Triazolo[4,3-a]pyrazine, 5,6,7,8-tetrahydro-3-(trifluoromethyl)-, monohydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-Retrahydro-[1,2,4]Triazolo[4,3-A]Pyrazine Hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-1,2,4-Triazolo-[4,3-Alpha] Pyrazine Hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro-[1,2,4]Traazoli[4,3-1]Pyrazine Hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro[1,2,4]Triazolo[4,3-A]Pyrazine
• 3-(Trifluoromethyl)-5,6,7,8-Tetrahydro[1,2,4]Triazolo[4,3-A]Pyrazine Hydrochloride (1:1)
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-(1,2,4)trazolo(4,3-a)pyrazine hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hcl
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
• 3-(Trifluoromethyl)-5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyrazine monohydrochloride
• 3-(trifluoromethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride
• IntermediateⅠof Sitagliptin phosphate
• Sitagliptin Intermediate
• Tap-4

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride

CAS: 762240-92-6

Formula: C₆H₇F₃N₄·HCl

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 228.60

Ref: 3B-T2998

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine hydrochloride, 98+%

CAS: 762240-92-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₈ClF₃N₄

Purity: 98+%

Molecular weight: 228.60

Ref: 02-H64993

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine, HCl

CAS: 762240-92-6

Formula: C₆H₈ClF₃N₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 228.6027

Ref: IN-DA0033H6

Sitagliptin Impurity 20 HCl

CAS: 762240-92-6

Formula: C₆H₇F₃N₄·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 192.15 36.46

Ref: 4Z-S-2013

Sitagliptin Intermediate 2

CAS: 762240-92-6

Sitagliptin Intermediate 2

Purity: ≥95%

Molecular weight: 228.603g/mol

Ref: 54-BUP19491

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride

CAS: 762240-92-6

Color and Shape: Neat

Ref: 86-MM3378.04

Sitagliptin Intermediate 2

CAS: 762240-92-6

Sitagliptin Intermediate 2 is a useful organic compound that has been used in life science related research.

Formula: C₆H₈ClF₃N₄

Purity: 98%

Color and Shape: Yellow-Brown Solid Crystalline

Molecular weight: 228.603

Ref: TM-T5903

5,6,7,8-Tetrahydro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

CAS: 762240-92-6

5,6,7,8-Tetrahydro-3-(trifluoromethyl)[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

Formula: C₆H₇F₃N₄·ClH

Purity: 98%

Color and Shape: white to off-white solid

Molecular weight: 228.60g/mol

Ref: 54-PC51048

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-d4 Hydrochloride

Controlled Product

CAS: 762240-92-6

Applications Isotope labelled Sitagliptin (S491000) intermediate.
References Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982) , Sarges, R., et al.: J. Med. Chem., 33, 2240 (1990), Cameron, M., et al.: J. Pharm. Biomed. Anal., 28, 137 (2002),

Formula: C₆H₃D₄F₃N₄·x(HCl)

Color and Shape: Neat

Molecular weight: 196.17 + x(36.46)

Ref: TR-T791812

Sitagliptin Triazole Hydrochloride

CAS: 762240-92-6

Formula: C₆H₇F₃N₄HCl

Molecular weight: 192.15 : 36.46

Ref: ST-EA-CP-S3004

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride

CAS: 762240-92-6

Inhibitor of DDP-4 peptidase

Formula: C₆H₇F₃N₄•HCl

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 228.6 g/mol

Ref: 3D-FT44582

3-Trifluoromethyl-5,6,7,8-tetrahydro-1,2,4-triazolo-[4,3-a]pyrazine hydrochloride

CAS: 762240-92-6

Formula: C₆H₈ClF₃N₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 228.6

Ref: 10-F076905

3-(Trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine Hydrochloride

CAS: 762240-92-6

Applications Sitagliptin intermediate.
References Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982), Sarges, R., et al.: J. Med. Chem., 33, 2240 (1990), Cameron, M., et al.: J. Pharm. Biomed. Anal., 28, 137 (2002),

Formula: C₆H₇F₃N₄·ClH

Color and Shape: White

Molecular weight: 228.60

Ref: TR-T791810