CAS 76265-39-9

izumenolide

Description:

Izumenolide, with the CAS number 76265-39-9, is a naturally occurring compound classified as a sesquiterpene lactone. It is primarily derived from various plant sources, particularly those in the Asteraceae family. This compound is characterized by its unique bicyclic structure, which contributes to its biological activity. Izumenolide exhibits a range of pharmacological properties, including anti-inflammatory, antimicrobial, and cytotoxic effects, making it of interest in medicinal chemistry and natural product research. Its mechanism of action often involves the modulation of cellular signaling pathways, which can lead to apoptosis in cancer cells. Additionally, izumenolide's potential applications in herbal medicine and as a lead compound for drug development are being explored. The compound is typically studied in the context of its chemical reactivity and interactions with biological systems, highlighting its significance in both synthetic and natural product chemistry. As with many sesquiterpene lactones, izumenolide may also possess allergenic properties, necessitating caution in its use.

Formula: C₄₀H₇₄O₁₄S₃

InChI: InChI=1/C40H74O14S3/c1-2-3-4-5-14-20-25-30-37(52-55(42,43)44)34-36-29-24-19-15-11-9-12-17-22-27-32-39(54-57(48,49)50)35-38(53-56(45,46)47)31-26-21-16-10-7-6-8-13-18-23-28-33-40(41)51-36/h2-3,28,33,36-39H,4-27,29-32,34-35H2,1H3,(H,42,43,44)(H,45,46,47)(H,48,49,50)/b3-2+,33-28+

Synonyms:

• Oxacyclotriacont-3-en-2-one, 16,18-bis(sulfooxy)-30-[2-(sulfooxy)-9-undecen-1-yl]-
• 16,18-Bis(sulfooxy)-30-[2-(sulfooxy)-9-undecenyl]-1-oxacyclotriacont-3-en-2-one
• izumenolide

Izumenolide

CAS: 76265-39-9

Izumenolide exhibits inhibitory effects on certain β-lactamases, with an IC50 concentration of 0.01 μg/mL specifically for TEM-2 β-lactamase.

Formula: C₄₀H₇₄O₁₄S₃

Color and Shape: Solid

Molecular weight: 875.202

Ref: TM-TN10073