CAS 76296-72-5

Polyphyllin D

Description:

Polyphyllin D is a steroidal saponin primarily derived from various plant species, particularly those in the genus Paris, such as Paris polyphylla. It is characterized by its complex glycosidic structure, which includes multiple sugar moieties attached to a steroid backbone. This compound exhibits a range of biological activities, including anti-inflammatory, anticancer, and immunomodulatory effects, making it of interest in pharmacological research. Polyphyllin D is known for its ability to induce apoptosis in cancer cells and may also enhance the efficacy of certain chemotherapeutic agents. Additionally, it has been studied for its potential role in traditional medicine, particularly in Asian herbal practices. The compound is typically extracted from plant sources and may require careful handling due to its bioactive properties. Its solubility and stability can vary depending on the solvent used, which is an important consideration for its application in research and potential therapeutic uses.

Formula: C₄₄H₇₀O₁₆

InChI: InChI=1S/C44H70O16/c1-19-8-13-44(53-18-19)20(2)30-27(60-44)15-26-24-7-6-22-14-23(9-11-42(22,4)25(24)10-12-43(26,30)5)55-41-36(52)38(59-39-35(51)33(49)31(47)21(3)54-39)37(29(17-46)57-41)58-40-34(50)32(48)28(16-45)56-40/h6,19-21,23-41,45-52H,7-18H2,1-5H3/t19-,20+,21+,23+,24-,25+,26+,27+,28+,29-,30+,31+,32+,33-,34-,35-,36-,37-,38-,39+,40+,41-,42+,43+,44-/m1/s1

InChI key: InChIKey=AWKXNOOUWFJCMU-WMRBLUSKSA-N

SMILES: C[C@@H]1[C@]2(O[C@@]3([C@]1([C@]4(C)[C@@](C3)([C@]5([C@](CC4)([C@]6(C)C(=CC5)C[C@@H](O[C@H]7[C@H](O)[C@@H](O[C@H]8[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O8)[C@H](O[C@@H]9O[C@@H](CO)[C@H](O)[C@H]9O)[C@@H](CO)O7)CC6)[H])[H])[H])[H])[H])CC[C@@H](C)CO2

Synonyms:

• (3β,25R)-Spirost-5-en-3-yl O-α-<span class="text-smallcaps">L</smallcap>-arabinofuranosyl-(1→4)-O-[6-deoxy-α-<smallcap>L</smallcap>-mannopyranosyl-(1→3)]-β-<smallcap>D</span>-glucopyranoside
• Chonglou Saponin II
• Polyphyllin D
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-α-<smallcap>L</smallcap>-arabinofuranosyl-(1→4)-O-[6-deoxy-α-<smallcap>L</span>-mannopyranosyl-(1→3)]-
• Polyphyllin II
• β-D-Glucopyranoside, (3β,25R)-spirost-5-en-3-yl O-α-L-arabinofuranosyl-(1→4)-O-[6-deoxy-α-L-mannopyranosyl-(1→3)]-
• (3β,25R)-Spirost-5-en-3-yl O-α-L-arabinofuranosyl-(1→4)-O-[6-deoxy-α-L-mannopyranosyl-(1→3)]-β-D-glucopyranoside

Chonglou Saponin II

CAS: 76296-72-5

Formula: C₄₄H₇₀O₁₆

Purity: 98%

Molecular weight: 855.0170

Ref: IN-DA00G43Z

Polyphyllin D

CAS: 76296-72-5

Formula: C₄₄H₇₀O₁₆

Molecular weight: 855.03

Ref: 7W-GY3951

Polyphyllin II

CAS: 76296-72-5

Polyphyllin II

Purity: ≥98%

Molecular weight: 855.02g/mol

Ref: 54-BUP02926

Polyphyllin D

CAS: 76296-72-5

Formula: C₄₄H₇₀O₁₆

Purity: 95%~99%

Molecular weight: 855.028

Ref: BP-BP1127

Polyphyllin II

Controlled Product

CAS: 76296-72-5

Applications Polyphylin II is a natural saponin extracted from the plant, Paris polyphylla, and displays antiproliferative activity in vivo.
References Ma, D. et al.: J. Int Med. Res., 37, 631 (2009); Yin, X. et al.: Biomed. Chrom., 27, 343 (2013);

Formula: C₄₄H₇₀O₁₆

Color and Shape: Neat

Molecular weight: 855.02

Ref: TR-P689460

Polyphyllin II

CAS: 76296-72-5

Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.

Formula: C₄₄H₇₀O₁₆

Purity: 99.92%

Color and Shape: Solid

Molecular weight: 855.02

Ref: TM-T3894

Polyphyllin II

CAS: 76296-72-5

Polyphyllin II is a steroidal saponin compound, which is derived from the rhizomes of the plant Paris polyphylla. This compound is part of a series of bioactive constituents commonly found in traditional Chinese herbal medicine. Its mode of action involves the disruption of cell membranes and induction of apoptosis, primarily through the modulation of various cellular signaling pathways. This includes the regulation of mitochondrial pathways, inhibition of cell proliferation, and the promotion of cancer cell death.

Formula: C₄₄H₇₀O₁₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 855.02 g/mol

Ref: 3D-FP73840