CAS 76326-31-3

2-Amino-5-phosphonovaleric acid

Description:

2-Amino-5-phosphonovaleric acid (CAS 76326-31-3) is a synthetic amino acid derivative that serves as a potent antagonist of the N-methyl-D-aspartate (NMDA) receptor, which is crucial in neurotransmission and synaptic plasticity in the central nervous system. This compound features a phosphonate group, which contributes to its biological activity and stability. It is characterized by its ability to inhibit excitatory neurotransmission, making it a valuable tool in neuropharmacological research. The molecular structure includes an amino group, a carboxylic acid group, and a phosphonate moiety, which collectively influence its solubility and reactivity. Typically, it is a white to off-white crystalline solid, soluble in water, and may exhibit a range of pH-dependent behaviors. Due to its role in modulating NMDA receptor activity, 2-amino-5-phosphonovaleric acid is studied for its potential therapeutic applications in conditions such as neurodegenerative diseases and cognitive disorders. However, its use in research requires careful handling due to its biological effects.

Formula: C₅H₁₂NO₅P

InChI: InChI=1S/C5H12NO5P/c6-4(5(7)8)2-1-3-12(9,10)11/h4H,1-3,6H2,(H,7,8)(H2,9,10,11)

InChI key: InChIKey=VOROEQBFPPIACJ-UHFFFAOYSA-N

SMILES: C(CC(C(O)=O)N)CP(=O)(O)O

Synonyms:

• (±)-2-Amino-5-phosphonopentanoic acid
• (±)-2-Amino-5-phosphonovaleric acid
• 2-Apv
• 2-Azaniumyl-5-phosphonopentanoate
• 5-Phosphono-<span class="text-smallcaps">DL</span>-norvaline
• 5-Phosphono-Dl-Norvaline
• 5-Phosphononorvaline
• <span class="text-smallcaps">DL</span>-2-Amino-5-phosphonopentanoic acid
• <span class="text-smallcaps">DL</span>-2-Amino-5-phosphonovaleric acid
• <span class="text-smallcaps">DL</span>-Norvaline, 5-phosphono-
• AP 5 (amino acid)
• DL-Norvaline, 5-phosphono-
• L-Norvaline, 5-phosphono-
• Norvaline, 5-phosphono-
• 5-phosphono-L-norvaline
• D-2-Amino-5-phosphopentanoic acid
• DL-2-Amino-5-phosphonovaleric acid

DL-2-Amino-5-phosphonopentanoic acid

CAS: 76326-31-3

Formula: C₅H₁₂NO₅P

Purity: 98%

Color and Shape: Solid

Molecular weight: 197.1262

Ref: IN-DA003MYH

DL-AP5

CAS: 76326-31-3

DL-AP5

Formula: C₅H₁₂NO₅P

Purity: ≥98%

Molecular weight: 197.13

Ref: 54-BUP01216

DL-2-Amino-5-phosphonopentanoic acid sodium salt

CAS: 76326-31-3

Molecular weight: 219.11

Ref: 7W-GM6357

DL-AP5

CAS: 76326-31-3

DL-AP5 is the racemic form of a selective N-methyl-D-aspartate (NMDA) receptor antagonist with anticonvulsant effects.

Formula: C₅H₁₂NO₅P

Purity: 99.33%

Color and Shape: Solid

Molecular weight: 197.1262

Ref: TM-T22733

DL-AP5

CAS: 76326-31-3

Antagonist of NMDA receptor

Formula: C₅H₁₂NO₅P

Purity: Min. 95%

Molecular weight: 197.13 g/mol

Ref: 3D-BD162539

DL-2-Amino-5-phosphonopentanoic Acid

Controlled Product

CAS: 76326-31-3

Applications DL-2-Amino-5-phosphonopentanoic Acid is a potent N-methyl-D-aspartate (NMDA) receptor antagonist.
References Davies, J., et al.: Brain Res., 235, 378 (1982); Evans, R.H., et al.: Br. J. Pharmacol., 75, 65 (1982)

Formula: C₅H₁₂NO₅P

Color and Shape: Neat

Molecular weight: 197.13

Ref: TR-A627550