CAS 76330-71-7

Altanserin

Description:

Altanserin is a chemical compound primarily recognized for its role as a selective serotonin 5-HT2A receptor antagonist. It is often utilized in pharmacological research, particularly in studies related to neuropharmacology and the investigation of psychiatric disorders. The compound has a complex molecular structure, which contributes to its specific binding affinity for the 5-HT2A receptor, making it a valuable tool in understanding serotonin-related pathways in the brain. Altanserin is typically characterized by its moderate lipophilicity, which influences its bioavailability and distribution within biological systems. Additionally, it is known for its potential applications in imaging studies, particularly in positron emission tomography (PET) to visualize serotonin receptor activity. Safety and toxicity profiles are essential considerations in its use, as with any pharmacological agent. Overall, Altanserin serves as an important compound in both therapeutic and research contexts, aiding in the exploration of serotonin's role in various neurological and psychiatric conditions.

Formula: C₂₂H₂₂FN₃O₂S

InChI: InChI=1S/C22H22FN3O2S/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)

InChI key: InChIKey=SMYALUSCZJXWHG-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC(=S)N1CCN3CCC(C(=O)C4=CC=C(F)C=C4)CC3)=CC=CC2

Synonyms:

• 278-422-1
• 3-(2-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone
• 3-{2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl}-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
• 4(1H)-quinazolinone, 3-[2-[4-(4-fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-
• 76330-71-7
• Altanserin
• Altanserin hydrochloride hydrate
• 3-(2-(4-(4-Fluorobenzoyl)-1-piperidinyl)ethyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinonehydrochloride
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrate hydrochloride
• AltanserineHCl
• ALTANSERIN HYDROCHLORIDE
• 3-[2-[4-(4-FLUOROBENZOYL)-1-PIPERIDINYL]ETHYL]-2,3-DIHYDRO-2-THIOXO-4(1H)-QUINAZOLINONE HYDROCHLORIDE
• 3-[2-[4-(4-Fluorobenzoyl)piperidin-1-yl]ethyl]-2-sulfanylidene-1H-quinazolin-4-one
• Altanserin hydrate hydrochloride
• 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrochloride hydrate

altanserin hydrochloride

CAS: 76330-71-7

Formula: C₂₂H₂₂FN₃O₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 411.4924

Ref: IN-DA0056E0

3-(2-(4-(4-Fluorobenzoyl)Piperidin-1-Yl)Ethyl)-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One

CAS: 76330-71-7

3-(2-(4-(4-Fluorobenzoyl)Piperidin-1-Yl)Ethyl)-2-Thioxo-2,3-Dihydroquinazolin-4(1H)-One

Purity: 99%

Molecular weight: 411.49g/mol

Ref: 54-PC108570

Altanserin hydrochloride hydrate

CAS: 76330-71-7

Formula: C₂₂H₂₂FN₃O₂S·HCl·xH₂O

Molecular weight: 447.95 (anhydrous)

Ref: 7W-GL6252

Altanserin

CAS: 76330-71-7

Altanserin, a 5-HT2A receptor binder, is tagged with F-18 for brain PET scans.

Formula: C₂₂H₂₂FN₃O₂S

Color and Shape: Solid

Molecular weight: 411.49

Ref: TM-T29913

Altanserin hydrochloride hydrate

CAS: 76330-71-7

Altanserin is a drug that binds to the 5-HT2 receptor and blocks its interactions with other molecules. Altanserin has been shown to have a synergic effect with antidepressants such as desipramine and fluoxetine, which are selective serotonin reuptake inhibitors (SSRIs). It has also been shown to inhibit the uptake of 5-HT in the brain, which may be related to its effect on locomotor activity. The use of altanserin for HIV infection is still being studied. One study found that altanserin reduced viral load and increased CD4+ T cell counts in HIV patients who were not taking any other anti-HIV drugs. A recent study found that altanserin at dosages up to 4mg/kg/day did not cause any toxic effects in rats.

Formula: C₂₂H₂₂FN₃O₂S•HCl•(H₂O)x

Purity: Min. 95%

Ref: 3D-BA183187

Altanserin

Controlled Product

CAS: 76330-71-7

Formula: C₂₂H₂₂FN₃O₂S

Color and Shape: Neat

Molecular weight: 411.492

Ref: TR-A585985

Altanserin

CAS: 76330-71-7

Altanserin is a drug that binds to the 5-HT2 receptor and blocks its interactions with other molecules. Altanserin has been shown to have a synergic effect with antidepressants such as desipramine and fluoxetine, which are selective serotonin reuptake inhibitors (SSRIs). It has also been shown to inhibit the uptake of 5-HT in the brain, which may be related to its effect on locomotor activity. The use of altanserin for HIV infection is still being studied. One study found that altanserin reduced viral load and increased CD4+ T cell counts in HIV patients who were not taking any other anti-HIV drugs. A recent study found that altanserin at dosages up to 4mg/kg/day did not cause any toxic effects in rats.

Purity: Min. 95%

Ref: 3D-FA41790