CAS 763924-54-5

Azithromycin Impurity O

CAS: 763924-54-5

The impurity O is a minor component found in the chromatographic purification of azithromycin. Impurity O is an antibiotic that has been shown to have antibacterial and anti-inflammatory properties. The impurity was first identified in the Chinese Pharmacopoeia and later included in the 2008 edition of the European Pharmacopoeia. Impurity O is produced by reacting aniline with sodium nitrite, followed by hydrolysis with sulfuric acid. The reaction produces 2-nitro-4-aminobenzoic acid, which can then be reduced to 2-amino-4-nitrobenzoic acid or oxidized to 4-aminobenzoate. Impurity O is found at a concentration of less than 0.1% in azithromycin preparations, but its biological activity has not been studied extensively.

Formula: C₃₉H₇₄N₂O₁₂

Purity: Min. 96 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 763.01 g/mol

Ref: 3D-FA76673

Azithromycin EP Impurity O

CAS: 763924-54-5

Formula: C₃₉H₇₄N₂O₁₂

Molecular weight: 763.02

Ref: ST-EA-CP-A37015

Azithromycin EP Impurity O

CAS: 763924-54-5

Formula: C₃₉H₇₄N₂O₁₂

Molecular weight: 763.04

Ref: 4Z-A-2611