CAS 764667-65-4: 1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1,3-butanedione

Formula: C₁₆H₁₂F₆N₄O₂

InChI: InChI=1S/C16H12F6N4O2/c17-10-6-12(19)11(18)4-8(10)3-9(27)5-14(28)25-1-2-26-13(7-25)23-24-15(26)16(20,21)22/h4,6H,1-3,5,7H2

InChI key: InChIKey=QAEDTLFWHIEVPK-UHFFFAOYSA-N

SMILES: O=C(N1CC2=NN=C(N2CC1)C(F)(F)F)CC(=O)CC3=CC(F)=C(F)C=C3F

Synonyms:

• (2Z)-1-[3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione
• 1,2,4-Triazolo[4,3-a]pyrazine, 7-[1,3-dioxo-4-(2,4,5-trifluorophenyl)butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-
• 1,3-Butanedione, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-
• 1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione
• 1-(3-Trifluoromethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)-4-(2,4,5-trifluoro-phenyl)-butan-1,3-dione
• 1-[3-(Trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butane-1,3-dione
• 1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-1,3-butanedione
• 4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butane-2-one
• 4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
• 7-[1,3-Dioxo-4-(2,4,5-trifluorophenyl)butyl]-3-trifluoromethyl-5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a]pyrazine
• Prositagliptin ketone

Sitagliptin Ketone (1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione)

CAS: 764667-65-4

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, …

• Formula: C₁₆H₁₂F₆N₄O₂
• Color and Shape: Beige Solid
• Molecular weight: 406.08644

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

CAS: 764667-65-4

• Formula: C₁₆H₁₂F₆N₄O₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 406.2825

Sitagliptin Impurity 42

CAS: 764667-65-4

• Formula: C₁₆H₁₂F₆N₄O₂
• Color and Shape: Pale Yellow Solid
• Molecular weight: 406.29

4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

CAS: 764667-65-4

Applications Sitagliptin intermediate. References Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982), Cameron, …

• Formula: C₁₆H₁₂F₆N₄O₂
• Color and Shape: Neat
• Molecular weight: 406.28

Sitagliptin keto amide impurity

CAS: 764667-65-4

Sitagliptin Keto Amide Impurity is a research and development impurity standard that has been shown …

• Formula: C₁₆H₁₂F₆N₄O₂
• Purity: Min. 95%
• Color and Shape: Slightly Yellow Powder
• Molecular weight: 406.28 g/mol

4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one-d4

CAS: 764667-65-4

Applications Isotope labelled Sitagliptin (S491000) intermediate. A dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for …

• Formula: C₁₆H₈D₄F₆N₄O₂
• Color and Shape: Neat
• Molecular weight: 410.31