CAS 76472-87-2

Kuwanon H

Description:

Kuwanon H is a natural compound classified as a flavonoid, specifically a type of chalcone. It is primarily derived from the root of the plant Morus alba, commonly known as white mulberry. This compound is recognized for its potential biological activities, including antioxidant, anti-inflammatory, and antimicrobial properties. Kuwanon H has been studied for its effects on various cellular processes, including its ability to modulate signaling pathways that may influence cancer cell proliferation and apoptosis. Additionally, it has shown promise in promoting skin health and may have applications in cosmetic formulations due to its protective effects against UV radiation. The compound's structure features a distinctive chalcone backbone, which contributes to its reactivity and interaction with biological systems. As with many natural products, further research is necessary to fully elucidate its mechanisms of action and potential therapeutic applications. Overall, Kuwanon H represents an interesting area of study within the field of natural product chemistry and pharmacology.

Formula: C₄₅H₄₄O₁₁

InChI: InChI=1S/C45H44O11/c1-21(2)6-10-27-33(48)15-14-29(41(27)53)42(54)38-31(26-12-8-24(46)18-34(26)49)16-23(5)17-32(38)39-36(51)20-37(52)40-43(55)30(11-7-22(3)4)44(56-45(39)40)28-13-9-25(47)19-35(28)50/h6-9,12-15,17-20,31-32,38,46-53H,10-11,16H2,1-5H3/t31-,32-,38-/m0/s1

InChI key: InChIKey=DKBPTKFKCCNXNH-QXGWMLRCSA-N

SMILES: OC=1C(=C2C(C(=O)C(CC=C(C)C)=C(O2)C3=C(O)C=C(O)C=C3)=C(O)C1)[C@@H]4[C@@H](C(=O)C5=C(O)C(CC=C(C)C)=C(O)C=C5)[C@@H](CC(C)=C4)C6=C(O)C=C(O)C=C6

Synonyms:

• Albanin G
• 8-[(1S,5R,6S)-6-[2,4-Dihydroxy-3-(3-methyl-2-buten-1-yl)benzoyl]-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one
• 4H-1-Benzopyran-4-one, 8-[6-[2,4-dihydroxy-3-(3-methyl-2-butenyl)benzoyl]-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-butenyl)-, [1S-(1α,5α,6β)]-
• 4H-1-Benzopyran-4-one, 8-[(1S,5R,6S)-6-[2,4-dihydroxy-3-(3-methyl-2-buten-1-yl)benzoyl]-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-buten-1-yl)-
• 4H-1-Benzopyran-4-one, 8-[(1S,5R,6S)-6-[2,4-dihydroxy-3-(3-methyl-2-butenyl)benzoyl]-5-(2,4-dihydroxyphenyl)-3-methyl-2-cyclohexen-1-yl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methyl-2-butenyl)-

8-[(1S,5R,6S)-6-[2,4-dihydroxy-3-(3-methylbut-2-enyl)benzoyl]-5-(2,4-dihydroxyphenyl)-3-methyl-1-cyclohex-2-enyl]-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-3-(3-methylbut-2-enyl)chromen-4-one

CAS: 76472-87-2

Formula: C₄₅H₄₄O₁₁

Purity: 95%

Molecular weight: 760.8243

Ref: IN-DA003AEJ

Kuwanon H

CAS: 76472-87-2

Kuwanon H

Purity: ≥95%

Molecular weight: 760.82g/mol

Ref: 54-BUP00225

Kuwanon H

CAS: 76472-87-2

Formula: C₄₅H₄₄O₁₁

Molecular weight: 760.84

Ref: 7W-GY7562

Kuwanon H

CAS: 76472-87-2

Formula: C₄₅H₄₄O₁₁

Purity: 95%~99%

Molecular weight: 760.836

Ref: BP-BP3603

Kuwanon H

CAS: 76472-87-2

Kuwanon H is a potent non-peptide GRP receptor antagonist with a Ki of 290 nM, useful in GRP-related studies.

Formula: C₄₅H₄₄O₁₁

Purity: 97.09% - 97.99%

Color and Shape: Solid

Molecular weight: 760.82

Ref: TM-TN1849

Kuwanon h

CAS: 76472-87-2

Oxygen-heterocyclic compound

Formula: C₄₅H₄₄O₁₁

Purity: ≥ 90.0 % (HPLC)

Molecular weight: 760.82

Ref: 5G-86208

Kuwanon H

Controlled Product

CAS: 76472-87-2

Kuwanon is a nonsteroidal anti-inflammatory drug that belongs to the class of acetate extract. It has been shown to have hypoglycemic effects in animal studies. Kuwanon H has been found to inhibit COX-2, an enzyme associated with inflammatory diseases and cancer. Kuwanon H also possesses potent anti-inflammatory activities and inhibits the production of proinflammatory cytokines such as TNF-α and IL-1β. This compound binds to receptors such as PPARγ and TRPA1, which are involved in inflammation and pain signaling pathways.

Formula: C₄₅H₄₄O₁₁

Purity: Min. 95%

Molecular weight: 760.82 g/mol

Ref: 3D-FK74401