CAS 765-87-7

1,2-Cyclohexanedione

Description:

1,2-Cyclohexanedione, with the CAS number 765-87-7, is a cyclic diketone characterized by its two carbonyl groups located on adjacent carbon atoms in a cyclohexane ring. This compound typically appears as a colorless to pale yellow liquid or solid, depending on temperature and purity. It is known for its ability to participate in various chemical reactions, including condensation and oxidation, making it a valuable intermediate in organic synthesis. The presence of two carbonyl groups contributes to its reactivity, allowing it to form enolates and engage in nucleophilic addition reactions. Additionally, 1,2-cyclohexanedione exhibits solubility in polar organic solvents, which enhances its utility in laboratory settings. Its structural features also allow for potential applications in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. However, like many diketones, it should be handled with care due to potential health hazards associated with inhalation or skin contact.

Formula: C₆H₈O₂

InChI: InChI=1S/C6H8O2/c7-5-3-1-2-4-6(5)8/h1-4H2

InChI key: InChIKey=OILAIQUEIWYQPH-UHFFFAOYSA-N

SMILES: O=C1C(=O)CCCC1

Synonyms:

• 1,2-Dioxocyclohexane
• Ai3-25042
• Brn 0507419
• Ccris 6296
• Cyclohexane-1,2-Dione
• NSC 627435
• Nsc 32950
• Cyclohexan-1,2-dione
• 1,2-Cyclohexanedione
• 4-07-00-01982 (Beilstein Handbook Reference)

1,2-Cyclohexanedione

CAS: 765-87-7

Formula: C₆H₈O₂

Purity: >97.0%(GC)

Color and Shape: White or Colorless to Light yellow to Light orange powder to lump to clear liquid

Molecular weight: 112.13

Ref: 3B-C0728

1,2-Cyclohexanedione, 98+%

CAS: 765-87-7

1,2-Cyclohexanedione is utilized as a substrate to study enzyme cyclohexane-1,2-dione hydrolase, which is a new tool to degrade alicyclic compounds. It also acts as a specific reagent for arginine residues. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product

Formula: C₆H₈O₂

Purity: 98+%

Color and Shape: Fused solid or clear liquid as melt, White to pale cream to pale yellow

Molecular weight: 112.13

Ref: 02-A14401

1,2-Cyclohexanedione

CAS: 765-87-7

Formula: C₆H₈O₂

Molecular weight: 112.13

Ref: 7W-GL7151

1,2-Cyclohexanedione

CAS: 765-87-7

1,2-Cyclohexanedione exhibits binding activity toward ketopantoyl-lactone reductase from Candida parapsilosis

Formula: C₆H₈O₂

Purity: 96.77%

Color and Shape: Yellow Solid

Molecular weight: 112.13

Ref: TM-T37384

Cyclohexane-1,2-dione

CAS: 765-87-7

Cyclohexane-1,2-dione

Formula: C₆H₈O₂

Purity: 95%

Color and Shape: colourless solid

Molecular weight: 112.12651g/mol

Ref: 54-OR0317

Cyclohexane-1,2-dione

CAS: 765-87-7

Cyclohexane-1,2-dione is a natural compound that can be found in kidney beans and other plants. It has been shown to inhibit the growth of tumor cells in vitro. Cyclohexane-1,2-dione binds to DNA polymerase, preventing replication and transcription. This reaction mechanism is similar to that of the rifamycins. Cyclohexane-1,2-dione has also been shown to bind enzymes such as nitrite ion reductase with high affinity and inhibit their activity. Cyclohexane-1,2-dione is chemically stable and does not react with metal ions or form stable complexes with biological molecules. The redox potentials for this molecule are -0.42 V (5/6) under aerobic conditions and -0.52 V (5/6) under anaerobic conditions.

Formula: C₆H₈O₂

Purity: Min. 96.5%

Color and Shape: Powder

Molecular weight: 112.13 g/mol

Ref: 3D-FC16073

1,2-Cyclohexanedione (exists as tautomeric mixture)

CAS: 765-87-7

Formula: C₆H₈O₂

Purity: 95%

Color and Shape: Solid, Low Melting Solid or Lumps

Molecular weight: 112.128

Ref: 10-F123100

1,2-Cyclohexanedione-d4

Controlled Product

CAS: 765-87-7

Applications 1,2-Cyclohexanedione-d4 is the isotope labelled analog of 1,2-Cyclohexanedione (C988085), a compound used as a substrate to study enzyme cyclohexane-1,2-dione hydrolase as a new tool to degrade alicyclic compounds.
References Fraas, S., et al.: J. Molec. Cataly. B. Enzy., 61, 47 (2009); Steinbach, A., et al.: FEBS. J., 279, 1209 (2012);

Formula: C₆D₄H₄O₂

Color and Shape: Neat

Molecular weight: 116.151

Ref: TR-C988087

1,2-Cyclohexanedione-13C6

Controlled Product

CAS: 765-87-7

Applications 1,2-Cyclohexanedione-13C6 is the isotope labelled analog of 1,2-Cyclohexanedione (C988085), a compound used as a substrate to study enzyme cyclohexane-1,2-dione hydrolase as a new tool to degrade alicyclic compounds.
References Fraas, S., et al.: J. Molec. Cataly. B. Enzy., 61, 47 (2009); Steinbach, A., et al.: FEBS. J., 279, 1209 (2012);

Formula: C₆H₈O₂

Color and Shape: Neat

Molecular weight: 118.082

Ref: TR-C988088