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CAS 76567-90-3

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thymidine 3':5'-cyclic monophosphate*sodium

Description:
Thymidine 3',5'-cyclic monophosphate sodium, commonly referred to as cyclic thymidine monophosphate (cTMP), is a nucleotide derivative characterized by its cyclic structure, which features a phosphate group linked to the 3' and 5' positions of the ribose sugar. This compound plays a significant role in cellular signaling and regulation, particularly in the context of cyclic nucleotide signaling pathways. As a sodium salt, it is soluble in water, making it suitable for various biochemical applications, including studies on enzyme activity and cellular processes. cTMP is involved in the modulation of various physiological functions, including cell proliferation and differentiation. Its cyclic nature allows it to act as a second messenger in signal transduction pathways, influencing the activity of protein kinases and other target proteins. In laboratory settings, it is often utilized in research related to molecular biology and pharmacology, particularly in the study of nucleic acid metabolism and the effects of cyclic nucleotides on cellular functions.
Formula:C10H13N2NaO7P
InChI:InChI=1/C10H13N2O7P.Na/c1-5-3-12(10(14)11-9(5)13)8-2-6-7(18-8)4-17-20(15,16)19-6;/h3,6-8H,2,4H2,1H3,(H,15,16)(H,11,13,14);
SMILES:Cc1cn(C2CC3C(COP(=O)(O)O3)O2)c(=O)nc1O.[Na]
Synonyms:
  • 2,4(1H,3H)-pyrimidinedione, 5-methyl-1-(tetrahydro-2-hydroxy-2-oxido-4H-furo[3,2-d]-1,3,2-dioxaphosphorin-6-yl)-, monosodium salt
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