CAS 765935-67-9

5-(1-piperazinyl)-2-benzofurancarboxylic acid ethyl ester hydrochloride

Description:

5-(1-Piperazinyl)-2-benzofurancarboxylic acid ethyl ester hydrochloride is a chemical compound characterized by its unique structure, which includes a benzofuran moiety and a piperazine ring. This compound typically appears as a white to off-white solid and is soluble in polar solvents such as water and ethanol, which is common for many hydrochloride salts. The presence of the piperazine group suggests potential pharmacological activity, as piperazine derivatives are often explored for their effects on the central nervous system and other biological targets. The ethyl ester functional group may enhance lipophilicity, potentially influencing the compound's absorption and distribution in biological systems. As a hydrochloride salt, it is likely to exhibit improved stability and solubility compared to its free base form. This compound may be of interest in medicinal chemistry and drug development, particularly in the context of designing new therapeutic agents. However, specific biological activities and safety profiles would require further investigation through empirical studies.

Formula: C₁₅H₁₈N₂O₃・HCl

Synonyms:

• Ethyl 5-(Piperazin-1-yl)-1-benzofuran-2-carboxylate HCl
• 5-(1-piperazinyl)-2-Benzofurancarboxylic acid ethyl ester Monohydrochloride
• Ethyl 5-(Piperazin-1-Yl)Benzofuran-2-Carboxylate Hydrochloride

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate hydrochloride

CAS: 765935-67-9

Formula: C₁₅H₁₉ClN₂O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 310.7760

Ref: IN-DA005WSL

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate hydrochloride

CAS: 765935-67-9

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate hydrochloride

Purity: 98%

Molecular weight: 310.78g/mol

Ref: 54-OR91100

Ethyl 5-(piperazin-1-yl)benzofuran-2-carboxylate hydrochloride

CAS: 765935-67-9

Purity: 98%

Molecular weight: 310.7799987792969

Ref: 10-F789390

Vilazodone Impurity 39 HCl

CAS: 765935-67-9

Formula: C₁₅H₁₈N₂O₃·HCl

Molecular weight: 274.32 36.46

Ref: 4Z-V-2146

5-(1-Piperazinyl)-2-benzofurancarboxylic Acid Ethyl Ester Hydrochloride

Controlled Product

CAS: 765935-67-9

Applications 5-(1-Piperazinyl)-2-benzofurancarboxylic Acid Ethyl Ester Hydrochloride is an intermediate in the synthesis of Vilazodone (V265000), a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.
References Hu, B., et al.: Org. Proc. Res. Develop., 16, 1552 (2012); Heinrich, T., et al.: J. Med. Chem., 47, 4684 (2004);

Formula: C₁₅H₁₉ClN₂O₃

Color and Shape: Neat

Molecular weight: 310.78

Ref: TR-P480630

Vilazodone Impurity-III

CAS: 765935-67-9

Formula: C₁₅H₁₈N₂O₃HCl

Molecular weight: 274.32 : 36.46

Ref: ST-EA-CP-V18039