CAS 766-63-2

2,4(1H,3H)-Pyrimidinedione-2-14C, 5-fluoro-

Description:

2,4(1H,3H)-Pyrimidinedione-2-14C, 5-fluoro- is a fluorinated pyrimidine derivative, characterized by its pyrimidine ring structure, which is a six-membered aromatic ring containing two nitrogen atoms at positions 1 and 3. This compound features a dione functional group, indicating the presence of two carbonyl (C=O) groups, which contribute to its reactivity and potential biological activity. The incorporation of a radioactive carbon isotope (14C) allows for tracing and studying metabolic pathways in biological systems. The 5-fluoro substitution enhances its pharmacological properties, making it relevant in medicinal chemistry, particularly in the development of antiviral and anticancer agents. The compound is typically used in research settings, especially in studies involving nucleic acid metabolism and the synthesis of nucleoside analogs. Safety precautions are necessary when handling this substance due to its radioactive nature, and it should be managed in accordance with regulations governing radioactive materials.

Formula: C₄H₃FN₂O₂

InChI: InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)/i4+2

InChI key: InChIKey=GHASVSINZRGABV-DOMIDYPGSA-N

SMILES: O=C1C(F)=CN[14C](=O)N1

Synonyms:

• 2,4(1H,3H)-Pyrimidinedione-2-14C, 5-fluoro-
• Uracil-2-14C, 5-fluoro-