CAS 76631-46-4

Detomidine

Description:

Detomidine is a potent sedative and analgesic agent primarily used in veterinary medicine, particularly for horses. It belongs to the class of alpha-2 adrenergic agonists, which function by inhibiting norepinephrine release, leading to sedation and analgesia. Detomidine is characterized by its rapid onset of action and relatively short duration of effects, making it suitable for various procedures requiring sedation. The substance is typically administered via intravenous or intramuscular routes. Its chemical structure includes a 2,6-dimethylphenyl moiety, contributing to its pharmacological properties. Detomidine is known for its ability to produce a state of calmness and reduced anxiety in animals, while also providing pain relief. However, it can cause side effects such as bradycardia, hypotension, and respiratory depression, necessitating careful monitoring during use. Due to its potency, detomidine is classified as a controlled substance in many regions, and its use is regulated to ensure safety and efficacy in veterinary practice.

Formula: C₁₂H₁₄N₂

InChI: InChI=1S/C12H14N2/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12/h3-5,7-8H,6H2,1-2H3,(H,13,14)

InChI key: InChIKey=RHDJRPPFURBGLQ-UHFFFAOYSA-N

SMILES: C(C1=C(C)C(C)=CC=C1)C2=CN=CN2

Synonyms:

• 1H-Imidazole, 4-((2,3-dimethylphenyl)methyl)-
• 1H-Imidazole, 5-[(2,3-dimethylphenyl)methyl]-
• 4-(2,3-Dimethyl-Benzyl)-1H-Imidazole
• 4-(2,3-Dimethylbenzyl)imidazol
• 5-(2,3-dimethylbenzyl)-1H-imidazole
• 5-[(2,3-Dimethylphenyl)methyl]-1H-imidazole
• Detomidina
• Detomidina [INN-Spanish]
• Detomidine [INN:BAN]
• Detomidinum
• Detomidinum [INN-Latin]
• Mpv 252Aii
• Unii-7N8K34P2Xh
• Detomidine

Detomidine Hydrochloride

CAS: 76631-46-4, 90038-01-0

Formula: C₁₂H₁₄N₂·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 222.72

Ref: 3B-D4331

5-[(2,3-dimethylphenyl)methyl]-1H-imidazole

CAS: 76631-46-4

Formula: C₁₂H₁₄N₂

Color and Shape: Solid

Molecular weight: 186.2530

Ref: IN-DA00G2FJ

Detomidine

Controlled Product

CAS: 76631-46-4

Applications Detomidine is a α-Adrenoceptor agonist with sedative and analgesic activity. Sedative.
References Laine, E., Acta Pharm. Suec., 20, 451 (1983); Virtanen, R., et al.: Eur. J. Pharmacol., 108, 163 (1985)

Formula: C₁₂H₁₄N₂

Color and Shape: Neat

Molecular weight: 186.25

Ref: TR-D297970

Detomidine

CAS: 76631-46-4

Detomidine is a nonnarcotic, synthetic α2-adrenergic agonist. Detomidine produces dose-dependent sedative and analgesic effects.

Formula: C₁₂H₁₄N₂

Purity: 98%

Color and Shape: White Crystalline Powder

Molecular weight: 186.25

Ref: TM-T22719