CAS 76639-94-6

Florfenicol

Description:

Florfenicol is a synthetic antibiotic belonging to the phenicol class, primarily used in veterinary medicine for the treatment of bacterial infections in livestock and aquaculture. It is characterized by its broad-spectrum activity against a variety of Gram-positive and Gram-negative bacteria, making it effective against pathogens that are resistant to other antibiotics. Florfenicol works by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit. This compound is known for its good tissue penetration and relatively low toxicity in animals, which contributes to its utility in treating infections. It is typically administered via injection or in feed formulations. Florfenicol is also notable for its ability to remain effective in the presence of certain bacterial resistance mechanisms, although its use is regulated in many countries due to concerns about antibiotic resistance and potential residues in food products. Overall, florfenicol represents an important tool in veterinary medicine, balancing efficacy with safety considerations.

Formula: C₁₂H₁₄Cl₂FNO₄S

InChI: InChI=1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1

InChI key: InChIKey=AYIRNRDRBQJXIF-NXEZZACHSA-N

SMILES: [C@@H]([C@H](NC(C(Cl)Cl)=O)CF)(O)C1=CC=C(S(C)(=O)=O)C=C1

Synonyms:

• 2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
• 2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
• 2,2-dichloro-N-{(1R,2S)-3-fluoro-1-hydroxy-1-[4-(methylsulfonyl)phenyl]propan-2-yl}acetamide
• 2,2-dichloro-N-{1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfanyl)phenyl]ethyl}acetamide
• Acetamide, 2,2-dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-
• Acetamide, 2,2-dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]-, [R-(R*,S*)]-
• Aquafen
• Aquaflor
• Flofenicol
• Flonicol
• Florfeniol
• Florgane
• Floron
• Nuflor
• Sch 25298
• Selectan
• Topazone

Florfenicol

CAS: 73231-34-2, 76639-94-6

Formula: C₁₂H₁₄Cl₂FNO₄S

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 358.21

Ref: 3B-F0811

Florfenicol

CAS: 76639-94-6

Florfenicol treats BRD in cattle, effective against Mannheimia, Pasteurella, Haemophilus, Fusobacterium, and Bacteroides.

Formula: C₁₂H₁₄Cl₂FNO₄S

Purity: 98.93%

Color and Shape: Solid

Molecular weight: 358.21

Ref: TM-T0454

Florfenicol

CAS: 76639-94-6

Florfenicol

Purity: ≥98%

Molecular weight: 358.21g/mol

Ref: 54-BUP18002