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CAS 7672-27-7

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N-omega-nitro-L-arginine benzyl ester*P-toluenesu

Description:
N-omega-nitro-L-arginine benzyl ester, commonly referred to as NNA, is a chemical compound that serves as a selective inhibitor of nitric oxide synthase (NOS). This compound is characterized by the presence of a nitro group attached to the arginine side chain, which enhances its inhibitory properties. The benzyl ester moiety contributes to its lipophilicity, facilitating membrane permeability and enhancing its biological activity. NNA is often utilized in biochemical research to study the role of nitric oxide in various physiological and pathological processes. Its ability to inhibit NOS makes it valuable in exploring cardiovascular functions, neurobiology, and inflammation. The compound is typically handled with care due to its potential toxicity and the need for proper safety protocols in laboratory settings. As with many chemical substances, its stability, solubility, and reactivity can vary depending on environmental conditions, such as pH and temperature. Overall, N-omega-nitro-L-arginine benzyl ester is a significant tool in pharmacological studies, particularly in the context of nitric oxide signaling pathways.
Formula:C13H19N5O4
InChI:InChI=1/C13H19N5O4/c14-11(7-4-8-16-13(15)17-18(20)21)12(19)22-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9,14H2,(H3,15,16,17)
SMILES:c1ccc(cc1)COC(=O)C(CCCNC(=N)NN(=O)=O)N
Synonyms:
  • Arg(NO2)-OBzl�TosOH
  • Arg(NO2)-OBzl.TosOH
  • benzyl (E)-N~5~-[amino(nitroamino)methylidene]-L-ornithinate
  • benzyl (E)-N~5~-[amino(nitroamino)methylidene]ornithinate
  • N-Omega-Nitro-L-Arginine Benzyl Ester P&
  • phenylmethyl (2S)-2-azanyl-5-[[azanyl(nitramido)methylidene]amino]pentanoate
  • (2S)-2-amino-5-[[amino(nitramido)methylene]amino]valeric acid benzyl ester
  • L-Ornithine, N5-[imino(nitroamino)methyl]-, phenylmethyl ester
  • n(w)-nitroargininebenzylester
  • phenylmethyl (2S)-2-amino-5-[[amino(nitramido)methylidene]amino]pentanoate
  • See more synonyms
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