CAS 767615-69-0

NQT Impurity E

Description:

NQT Impurity E, identified by the CAS number 767615-69-0, is a chemical substance that is often associated with pharmaceutical research and development. While specific details about its molecular structure and properties may not be widely available, impurities like NQT Impurity E are typically characterized by their role in affecting the purity and efficacy of active pharmaceutical ingredients (APIs). Such impurities can arise during the synthesis of drugs and may influence the stability, safety, and overall performance of the final product. In general, impurities are analyzed for their chemical composition, potential toxicity, and interaction with other components in formulations. Regulatory agencies often require thorough characterization and quantification of impurities to ensure compliance with safety standards. Understanding the characteristics of impurities like NQT Impurity E is crucial for pharmaceutical companies to maintain product quality and adhere to regulatory guidelines.

3-O-Cyclopropylmethylnaltrexone

Controlled Product

CAS: 767615-69-0

Applications 3-O-Cyclopropylmethylnaltrexone is a metabolite of Naltrexone (N285750); a nonselective opioid receptor antagonist, a congener of Naloxone.
References Maickel, R.P., et al.: Ann. N.Y. Acad. Sci., 281, 321 (1976); Gritz, E.R., et al.: Clin. Pharmacol. Ther. 19, 773 (1976); Gonzales, J.P., et al.: Drugs, 35, 192 (1988); Berg, B.J., et al.: Drug Saf., 15, 274 (1996)

Formula: C₂₄H₂₉NO₄

Color and Shape: Neat

Molecular weight: 395.49

Ref: TR-C989360

3-O-Cyclopropylmethylnaltrexone (1 mg/ml in Acetonitrile)

Controlled Product

CAS: 767615-69-0

Formula: C₂₄H₂₉NO₄

Color and Shape: Single Solution

Molecular weight: 395.49

Ref: TR-KIT3885

3-O-Cyclopropylmethylnaltrexone-d3

Controlled Product

CAS: 767615-69-0

Formula: C₂₄D₃H₂₆NO₄

Color and Shape: Neat

Molecular weight: 398.51

Ref: TR-C989362

Naltrexone EP Impurity E

CAS: 767615-69-0

Formula: C₂₄H₂₉NO₄

Molecular weight: 395.5

Ref: ST-EA-CP-N57005

Naltrexone impurity E

Controlled Product

CAS: 767615-69-0

Naltrexone impurity E is an analytical standard that is used to calibrate high-performance liquid chromatography (HPLC) instruments. This substance is a natural metabolite of naltrexone, which is an opioid receptor antagonist, and has the chemical name of 4-hydroxy-3-methoxy-N-(5α,6β)-dimethyl-2-[(1R)-1-(3-methyloxetan-3-yl)piperidin-4-yl] benzeneacetamide. Naltrexone impurity E is a pharmacopoeia grade compound that can be used in the synthesis of drug products. Custom synthesis and natural or synthetic sources are available.

Formula: C₂₄H₂₉NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 395.49 g/mol

Ref: 3D-IN167083