CAS 76792-96-6

(-)-4-Hydroxypropranolol

Description:

(-)-4-Hydroxypropranolol is a beta-blocker that is primarily used in the treatment of cardiovascular conditions such as hypertension and anxiety. It is a chiral compound, with the "(-)" indicating its specific enantiomeric form, which is biologically active. The substance features a phenolic hydroxyl group, which contributes to its pharmacological properties, and a propanolamine side chain that is characteristic of beta-blockers. Its mechanism of action involves the inhibition of beta-adrenergic receptors, leading to decreased heart rate and reduced myocardial contractility. This compound is known for its ability to cross the blood-brain barrier, which can influence its effects on anxiety and other central nervous system-related conditions. In terms of physical properties, (-)-4-Hydroxypropranolol is typically a white to off-white crystalline solid, soluble in water and organic solvents. Safety and efficacy profiles are well-documented, making it a valuable therapeutic agent in clinical practice. As with all medications, it is important to consider potential side effects and contraindications when prescribing or using this compound.

Formula: C₁₆H₂₁NO₃

InChI: InChI=1S/C16H21NO3/c1-11(2)17-9-12(18)10-20-16-8-7-15(19)13-5-3-4-6-14(13)16/h3-8,11-12,17-19H,9-10H2,1-2H3/t12-/m0/s1

InChI key: InChIKey=CWEPACWBWIOYID-LBPRGKRZSA-N

SMILES: O(C[C@H](CNC(C)C)O)C=1C2=C(C(O)=CC1)C=CC=C2

Synonyms:

• (-)-4-Hydroxypropranolol
• (-)-Hydroxypropranolol
• (S)-4-Hydroxypropranolol
• 1-Naphthalenol,4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-, (S)-
• 4-[(2S)-2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-1-naphthalenol
• 1-Naphthalenol, 4-[(2S)-2-hydroxy-3-[(1-methylethyl)amino]propoxy]-

(S)-4-Hydroxy propranolol hydrobromide

CAS: 76792-96-6

(S)-4-Hydroxy propranolol hydrobromide is an enantiomer of propranolol. It is a beta blocker that blocks the action of the neurotransmitter noradrenaline. The (S)-enantiomer of propranolol has been shown to be more potent in inhibiting the release of noradrenaline from nerve endings than the (R)-enantiomer and also to have a longer duration of action. This product is used as an antihypertensive agent and for beta-blockade during myocardial infarction. It can be used in assays to assess drug metabolism, quantify alprenolol, or assess the effects on carbon source, ionic environment, and fluorescence by measuring changes in pH.

Formula: C₁₆H₂₂BrNO₃

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 356.25 g/mol

Ref: 3D-FH24111