CAS 76811-98-8

2-[4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]phenyl]-2,2-dimethylacetic acid

Description:

2-[4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]phenyl]-2,2-dimethylacetic acid, with CAS number 76811-98-8, is a complex organic compound characterized by its multi-functional structure. It features a piperidine ring, which contributes to its potential biological activity, and a hydroxydiphenylmethyl group that may enhance its interaction with biological targets. The presence of a dimethylacetic acid moiety suggests that it may exhibit acidic properties, which can influence its solubility and reactivity in various environments. This compound is likely to be lipophilic due to its aromatic and aliphatic components, which may affect its pharmacokinetics if used in medicinal chemistry. Additionally, the presence of multiple functional groups indicates potential for hydrogen bonding and other intermolecular interactions, which could be relevant in drug design and development. Overall, this compound's unique structure may confer specific biological activities, making it of interest in pharmaceutical research.

Formula: C₃₂H₃₇NO₄

InChI: InChI=1S/C32H37NO4/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28,37H,9,14,19-23H2,1-2H3,(H,35,36)

InChI key: InChIKey=NGAKDIWPTMPPFP-UHFFFAOYSA-N

SMILES: C(O)(C1CCN(CCCC(=O)C2=CC=C(C(C(O)=O)(C)C)C=C2)CC1)(C3=CC=CC=C3)C4=CC=CC=C4

Synonyms:

• 2-(4-(4-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoic acid
• 2-[4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]phenyl]-2,2-dimethylacetic acid
• 4-[1-Oxo-4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]butyl]-α,α-dimethylbenzeneacetic acid
• 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethylbenzeneacetic acid
• 4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethylphenylacetic acid
• Benzeneacetic acid, 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethyl-
• Fexofenadinone

FEXOFENADINE IMPURITY A CRS

CAS: 76811-98-8

FEXOFENADINE IMPURITY A CRS

Ref: 41-Y0000751

Fexofenadine Related Compound A (2-(4-{4-[4-(Hydroxydiphenylmethyl)piperidin-1-yl]butanoyl}phenyl)-2-methylpropanoic acid)

CAS: 76811-98-8

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₃₂H₃₇NO₄

Color and Shape: White Powder

Molecular weight: 499.27226

Ref: 45-1270388

Fexofenadinone

CAS: 76811-98-8

Formula: C₃₂H₃₇NO₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 499.6405

Ref: IN-DA00G28H

Fexofenadine EP Impurity A (Fexofenadine USP Related Compound A)

CAS: 76811-98-8

Formula: C₃₂H₃₇NO₄

Color and Shape: White To Off-White Solid

Molecular weight: 499.65

Ref: 4Z-F-0413

2-(4-(4-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoic acid (Fexofenadine Impurity)

CAS: 76811-98-8

2-(4-(4-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoic acid (Fexofenadine Impurity)

Purity: 98%

Ref: 54-OR1037283

2-[4-[4-[4-(Hydroxydiphenylmethyl)piperidin-1-yl]butanoyl]phenyl]-2-methylpropanoic Acid (Ketofexofenadine)

Controlled Product

CAS: 76811-98-8

Formula: C₃₂H₃₇NO₄

Color and Shape: Neat

Molecular weight: 499.64

Ref: 86-MM0507.01

Fexofenadinone

Controlled Product

CAS: 76811-98-8

Impurity Fexofenadine EP Impurity A
Stability Hygroscopic
Applications The oxo analogue of Fexofenadine (F322470); H1-histamine receptor antagonist and an active metabolite of Terfenadine (T114500).
References Radhakrishna, T. et al.: J. Pharmac. Biomed. Anal., 29, 681 (2002); Chen, T.M. et al.: J. Pharmac. Biomed, Anal., 9, 929 (1991);

Formula: C₃₂H₃₇NO₄

Color and Shape: Neat

Molecular weight: 499.64

Ref: TR-F322520

Fexofenadine EP Impurity A

CAS: 76811-98-8

Formula: C₃₂H₃₇NO₄

Molecular weight: 499.65

Ref: ST-EA-CP-F13001

Fexofenadinone Hydrochloride

Controlled Product

CAS: 76811-98-8

Applications The oxo analogue of Fexofenadine (F322470); H1-histamine receptor antagonist and an active metabolite of Terfenadine (T114500).
References Radhakrishna, T. et al.: J. Pharmac. Biomed. Anal., 29, 681 (2002); Chen, T.M. et al.: J. Pharmac. Biomed, Anal., 9, 929 (1991);

Formula: C₃₂H₃₇NO₄•(HCl)x

Color and Shape: Neat

Molecular weight: 536.1

Ref: TR-F322563

4-((4-(4-Hydroxydiphenylmethyl)-1-piperidinyl)-1-oxobutyl)-a,a-dimethyl-phenylacetic acid

CAS: 76811-98-8

Methyl ester of 4-((4-(4-hydroxydiphenylmethyl)-1-piperidinyl)-1-oxobutyl)-a,a-dimethylphenylacetic acid is a metabolite of lisinopril. It has been used to calibrate the flow rate of chromatographic methods by comparison with anhydrous standards. The methyl ester can be quantitatively converted to the sodium salt by photolysis in a diode laser. This method has been validated and found to be accurate for industrial process monitoring.

Formula: C₃₂H₃₇NO₄

Purity: Min. 95%

Molecular weight: 499.64 g/mol

Ref: 3D-FF153455