CAS 76822-34-9

Anisodine hydrobromide

Description:

Anisodine hydrobromide is a chemical compound that belongs to the class of anticholinergic agents, primarily used for its pharmacological effects. It is a quaternary ammonium salt derived from anisodine, which is an alkaloid obtained from the plant species of the Solanaceae family. The compound is characterized by its ability to inhibit the action of acetylcholine at muscarinic receptors, leading to effects such as reduced secretions, bronchodilation, and relaxation of smooth muscles. Anisodine hydrobromide is often utilized in medical settings for its potential to alleviate symptoms associated with respiratory conditions and to provide muscle relaxation during surgical procedures. Its solubility in water and stability under standard conditions make it suitable for various formulations. However, like many anticholinergic agents, it may have side effects, including dry mouth, blurred vision, and urinary retention, necessitating careful monitoring during use. As with any pharmacological agent, its application should be guided by clinical judgment and consideration of patient-specific factors.

Formula: C₁₇H₂₁NO₅·BrH

InChI: InChI=1S/C17H21NO5.BrH/c1-18-12-7-11(8-13(18)15-14(12)23-15)22-16(20)17(21,9-19)10-5-3-2-4-6-10;/h2-6,11-15,19,21H,7-9H2,1H3;1H/t11-,12-,13+,14-,15+,17-;/m1./s1

InChI key: InChIKey=GJPDCORRBGIJOP-JYHRPVKFSA-N

SMILES: CN1[C@@]2([C@]3([C@](O3)([C@]1(C[C@@H](OC([C@](CO)(O)C4=CC=CC=C4)=O)C2)[H])[H])[H])[H].Br

Synonyms:

• (1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl (2S)-2,3-dihydroxy-2-phenylpropanoate
• (1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl (2S)-2,3-dihydroxy-2-phenylpropanoate hydrobromide (1:1)
• 3-Oxa-9-azatricyclo[3.3.1.0^2,4]nonane, benzeneacetic acid deriv.
• Anisodine Hydrobromide 96%, 99%
• Benzeneacetic acid, α-hydroxy-α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, hydrobromide (1:1), (αS)-
• Benzeneacetic acid, α-hydroxy-α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, hydrobromide, (αS)-
• Benzeneacetic acid, α-hydroxy-α-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.0^2,4]non-7-yl ester, hydrobromide, [7(S)-(1α,2β,4β,5α,7β)]-
• Benzeneacetic acid, α-hydroxy-α-(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide, [7(S)-(1α,2β,4β,5α,7β)]-
• Benzeneacetic acid, α-hydroxy-α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide (1:1), (αS)-
• Benzeneacetic acid, α-hydroxy-α-(hydroxymethyl)-, (1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide, (αS)-
• Anisodine hydrobromide

(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-yl (S)-2,3-dihydroxy-2-phenylpropanoate hydrobromide

CAS: 76822-34-9

Formula: C₁₇H₂₂BrNO₅

Purity: %

Color and Shape: Solid

Molecular weight: 400.2643

Ref: IN-DA019FUY

Anisodine-13C-d3

CAS: 76822-34-9

Formula: C₁₆₁₃CH₁₈D₃NO₅

Molecular weight: 323.368

Ref: 4Z-A-311010

Anisodine hydrobromide

CAS: 76822-34-9

Natural alkaloid

Formula: C₁₇H₂₁NO₅HBr

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 400.27

Ref: 5G-89564

Anisodine Hydrobromide

Controlled Product

CAS: 76822-34-9

Applications Hydrobromide salt of Anisodine a belladonna alkaloid. Acts as an anticholinergic agent.
References Kai, G. et al.: Mol. Biosyst. 8, 2883 (2012);

Formula: C₁₇H₂₂BrNO₅

Color and Shape: Neat

Molecular weight: 400.26

Ref: TR-A673700

Anisodine hydrobromide

CAS: 76822-34-9

Anisodine hydrobromide is a compound that modulates transcriptional regulation. It has been shown to inhibit the proliferation of cultured human renal proximal cells and to reduce the development of kidney fibrosis in rats. Anisodine also inhibits locomotor activity and improves sample preparation in a statistically significant way. Anisodine hydrobromide has not been found to be toxic at doses up to 2000 mg/kg, which is its highest dose studied so far. The study used an experimental model of neurotrophic factors, soybean extract and fluorescein angiography with LC-MS/MS method as the analytical technique.

Formula: C₁₇H₂₂BrNO₅

Purity: Min. 98%

Color and Shape: Powder

Molecular weight: 400.26 g/mol

Ref: 3D-FA148900

Anisodine Hydrobromide

CAS: 76822-34-9

Formula: C₁₇H₂₁NO₅HBr

Molecular weight: 319.36 : 80.91

Ref: ST-EA-CP-A331002

Anisodine hydrobromide

CAS: 76822-34-9

Anisodine hydrobromide is an inhibitor of adenosine kinase.

Formula: C₁₇H₂₂BrNO₅

Color and Shape: White Crystals Or Crystalline Powder

Molecular weight: 400.27

Ref: TM-T21018