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CAS 76824-35-6

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Famotidine

Description:
Famotidine is a histamine H2 receptor antagonist primarily used to treat conditions related to excessive stomach acid, such as gastroesophageal reflux disease (GERD) and peptic ulcers. It works by inhibiting the action of histamine on the H2 receptors of gastric parietal cells, thereby reducing gastric acid secretion. Famotidine is characterized by its chemical formula C8H10N8O2S, and it has a molecular weight of approximately 337.43 g/mol. The substance appears as a white to off-white crystalline powder, which is soluble in water and slightly soluble in alcohol. Famotidine is typically administered orally and is available in various formulations, including tablets and oral suspension. Its pharmacokinetics include rapid absorption, with peak plasma concentrations occurring within a few hours after administration. Famotidine is generally well-tolerated, with common side effects including headache, dizziness, and gastrointestinal disturbances. It is important to note that famotidine may interact with other medications, so a healthcare provider should be consulted before use.
Formula:C8H15N7O2S3
InChI:InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
InChI key:InChIKey=XUFQPHANEAPEMJ-UHFFFAOYSA-N
SMILES:N(C(=N)N)C1=NC(CSCCC(NS(N)(=O)=O)=N)=CS1
Synonyms:
  • 3-[(2-Diaminomethyleneaminothiazol-4-yl)methylthio]-N-sulfamoylpropionamidine
  • 3-[([2-[(Diaminomethylidene)amino]-1,3-thiazol-4-yl]methyl)sulfanyl]-N-sulfamoylpropanimidamide
  • 3-[({2-[(Hydrazonomethyl)amino]thiazol-4-yl}methyl)thio]-N-sulfamoylpropionamidine
  • 3-[[2-(Diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N′-sulfamoylpropanimidamide
  • 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)propanimidamide
  • Agufam
  • Amfamox
  • Antodine
  • Apo-Famotidine
  • Apogastine
  • See more synonyms
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