CAS 76902-49-3
:Adenosine,N-benzoyl-3'-deoxy- (9CI)
Description:
Adenosine, N-benzoyl-3'-deoxy- (9CI), with the CAS number 76902-49-3, is a modified nucleoside derivative of adenosine. This compound features a benzoyl group attached to the nitrogen atom of the adenosine structure, which enhances its lipophilicity and may influence its biological activity. The "3'-deoxy" designation indicates that the hydroxyl group at the 3' position of the ribose sugar is absent, which can affect the compound's interactions with nucleic acid structures and enzymes. Typically, such modifications can alter the pharmacokinetic properties, stability, and binding affinity of the molecule in biological systems. Adenosine derivatives are often studied for their potential therapeutic applications, including roles in cellular signaling, anti-inflammatory effects, and modulation of neurotransmission. The compound's characteristics, such as solubility, melting point, and reactivity, would depend on its specific structural features and the presence of functional groups. As with many nucleoside analogs, it may also exhibit unique interactions with biological targets, making it of interest in medicinal chemistry and drug development.
Formula:C17H17N5O4
Synonyms:- N6-Benzoyl-3’-Deoxyadenosine
- N-(9-((2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)benzamide
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Found 2 products.
N6-Benzoyl-3'-deoxyadenosine
CAS:N6-Benzoyl-3'-deoxyadenosine is a nucleoside analogue that is used as a substrate for DNA polymerase. The efficiency of this compound has been shown to be higher than other nucleotides. In addition, N6-Benzoyl-3'-deoxyadenosine has been shown to be an efficient donor in the ligation reaction and can also act as a competitive inhibitor of topoisomerase II. N6-Benzoyl-3'-deoxyadenosine is a scissile substrate for DNA topoisomerase II and cleaves at the same site as dATP. This compound has been shown to be active against both Gram-positive bacteria and Mycobacterium tuberculosis with high selectivity.Formula:C17H17N5O4Purity:Min. 95%Molecular weight:355.35 g/mol
