CAS 7693-46-1

4-Nitrophenyl chloroformate

Description:

4-Nitrophenyl chloroformate, with the CAS number 7693-46-1, is an organic compound that serves as an important reagent in organic synthesis, particularly in the formation of carbamates. It is characterized by its structure, which includes a nitro group (-NO2) attached to a phenyl ring, and a chloroformate group (-O-C(=O)-Cl). This compound typically appears as a yellow to orange crystalline solid and is known for its reactivity, particularly with nucleophiles, due to the electrophilic nature of the carbonyl carbon in the chloroformate moiety. It is soluble in organic solvents such as dichloromethane and ethyl acetate but is less soluble in water. 4-Nitrophenyl chloroformate is sensitive to moisture and should be handled with care, as it can release toxic gases upon hydrolysis. Its applications extend to the synthesis of various pharmaceuticals and agrochemicals, making it a valuable tool in synthetic organic chemistry. Proper safety precautions should be taken when handling this compound due to its potential hazards.

Formula: C₇H₄ClNO₄

InChI: InChI=1S/C7H4ClNO4/c8-7(10)13-6-3-1-5(2-4-6)9(11)12/h1-4H

InChI key: InChIKey=NXLNNXIXOYSCMB-UHFFFAOYSA-N

SMILES: O(C(Cl)=O)C1=CC=C(N(=O)=O)C=C1

Synonyms:

• (4-Nitrophenoxy)carbonyl chloride
• (p-Nitrophenoxy)carbonyl chloride
• 4-Nitrophenyl Chloroformate
• 4-Nitrophenyl carbonochloridate
• 4-Nitrophenyl chlorocarbonate
• 4-Nitrophenylchlorformiat
• Chloroformate, 4-Nitrophenyl
• Chloroformiate de 4-nitrophenyle
• Chloroformic acid 4-nitrophenyl ester
• Chloroformic acid p-nitrophenyl ester
• Cloroformiato De 4-Nitrofenilo
• Formic acid, chloro-, p-nitrophenyl ester
• Hypochlorous acid, 4-nitrophenyl ester
• p-Nitrophenol chloroformate
• p-Nitrophenolchloroformate
• p-Nitrophenyl chlorocarbonate
• p-Nitrophenyl chloroformate
• p-Nitrophenoxycarbonyl chloride
• Carbonochloridic acid, 4-nitrophenyl ester
• 4-nitrophenylchloroformate
• carbonochloridic acid, 4-nitrophenyl ester

4-Nitrophenyl Chloroformate

CAS: 7693-46-1

Formula: C₇H₄ClNO₄

Purity: >98.0%(T)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 201.56

Ref: 3B-C1400

4-Nitrophenyl chloroformate

CAS: 7693-46-1

Formula: C₇H₄ClNO₄

Purity: 97.5%

Color and Shape: Solid

Molecular weight: 201.5640

Ref: IN-DA0036N6

4-Nitrophenyl chloroformate

CAS: 7693-46-1

Formula: C₇H₄ClNO₄

Molecular weight: 201.57

Ref: 7W-GK6866

4-Nitrophenyl chloroformate

CAS: 7693-46-1

Formula: C₇H₄ClNO₄

Purity: 90.0%

Color and Shape: Solid

Molecular weight: 201.56

Ref: 10-F038189

4-Nitrophenyl chloroformate

CAS: 7693-46-1

4-Nitrophenyl chloroformate

Formula: C₇H₄ClNO₄

Purity: 95%

Color and Shape: off white crystalline solid

Molecular weight: 201.56396g/mol

Ref: 54-OR11227

4-Nitrophenyl Chloroformate >90%

Controlled Product

CAS: 7693-46-1

Stability Moisture Sensitive
Applications 4-Nitrophenyl Chloroformate is an ester of chloroformic acid used in the immobilization of enzymes and other biomolecules.
References Scouten, W.H, et al.: Ann. N.Y. Acad. Sci., 750, 391 (1995); Mikulec, L.J. et al.: J. Biomed. Mat. Res., 32, 203 (1996);

Formula: C₇H₄ClNO₄

Purity: >90%

Color and Shape: Off White Powder

Molecular weight: 201.564

Ref: TR-N503310

4-Nitrophenyl chloroformate

CAS: 7693-46-1

4-Nitrophenyl chloroformate is a reagent used for the treatment of wastewater. It is used to remove organic contaminants from water by forming ester hydrochlorides with these contaminants. The reaction mechanism of 4-nitrophenyl chloroformate involves a nucleophilic substitution reaction, which proceeds via an electrophilic addition reaction. This compound has been shown to have pharmacokinetic properties in rats and mice, as well as being activated by integrin receptor kinase and displaying kinetic behaviour. 4-Nitrophenyl chloroformate also has optical sensor activity and can be used as a cyclic peptide.

Formula: C₇H₄ClNO₄

Purity: Min. 95%

Color and Shape: Off-White Yellow Powder

Molecular weight: 201.56 g/mol

Ref: 3D-FN00094

4-Nitrophenyl chloroformate, 97%

CAS: 7693-46-1

4-Nitrophenyl chloroformate is used in the synthesis of poly(oxyethylene) modified dextrans. It is also used to prepare a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA. Further, it is used in the synthesis of mixed, activated carbonates, thioca

Formula: C₇H₄ClNO₄

Purity: 97%

Color and Shape: Crystals or powder or crystalline powder or fused solid, White to cream to pale gray

Molecular weight: 201.56

Ref: 02-A18742