CAS 76948-72-6

Cleomiscosin A

Description:

Cleomiscosin A is a natural compound classified as a flavonoid, specifically a type of prenylated flavonoid. It is primarily derived from the plant Cleome viscosa, which is known for its traditional medicinal uses. This compound exhibits a range of biological activities, including antioxidant, anti-inflammatory, and potential anticancer properties, making it of interest in pharmacological research. Cleomiscosin A is characterized by its unique chemical structure, which includes a flavone backbone with prenyl groups that enhance its biological activity. The compound is typically studied for its effects on various cellular pathways and its potential therapeutic applications. Additionally, its solubility and stability can vary depending on the solvent and environmental conditions, which are important factors to consider in experimental settings. Overall, Cleomiscosin A represents a significant area of study in natural product chemistry and its implications in health and disease.

Formula: C₂₀H₁₈O₈

InChI: InChI=1/C20H18O8/c1-24-13-7-10(3-5-12(13)22)17-15(9-21)26-20-18-11(4-6-16(23)27-18)8-14(25-2)19(20)28-17/h3-8,15,17,21-22H,9H2,1-2H3/t15-,17-/s2

InChI key: InChIKey=OCBGWPJNUZMLCA-OLKMYRHANA-N

SMILES: O(C)C=1C2=C(C3=C(C1)C=CC(=O)O3)O[C@H](CO)[C@H](O2)C4=CC(OC)=C(O)C=C4

Synonyms:

• (2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-2,3-dihydro-9H-[1,4]dioxino[2,3-h]chromen-9-one
• (2S,3S)-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-methoxy-2,3-dihydro-9H-[1,4]dioxino[2,3-h]chromen-9-one
• (2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-2,3-dihydro-9H-[1,4]dioxino[2,3-h]chromen-9-one
• 9H-Pyrano(2,3-f)-1,4-benzodioxin-9-one, 2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-methoxy-, trans-(+-)-
• 9H-Pyrano(2,3-f)-1,4-benzodioxin-9-one, 2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-, trans-(+-)-
• 9H-Pyrano[2,3-f]-1,4-benzodioxin-9-one, 2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-, (2R,3R)-rel-
• 9H-pyrano[2,3-f]-1,4-benzodioxin-9-one, 2,3-dihydro-2-(4-hydroxy-3-methoxyphenyl)-3-(hydroxymethyl)-5-methoxy-, (2S,3S)-
• Cleomiscosin A
• NSC 346197
• rel-(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-9H-pyrano[2,3-f]-1,4-benzodioxin-9-one

rel-(2R,3R)-2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-5-methoxy-9H-pyrano[2,3-f]-1,4-benzodioxin-9-one

CAS: 76948-72-6

Formula: C₂₀H₁₈O₈

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 386.3521

Ref: IN-DA00G60V

Cleomiscosin A

CAS: 76948-72-6

Cleomiscosin A

Purity: ≥98%

Molecular weight: 386.35g/mol

Ref: 54-BUP07335

Cleomiscosin A

CAS: 76948-72-6

Cleomiscosin A, from Acer okamotoanum, inhibits mouse TNF-α and may prevent LDL oxidation in atherosclerosis.

Formula: C₂₀H₁₈O₈

Purity: 99.85%

Color and Shape: Solid

Molecular weight: 386.35

Ref: TM-TN1511

Cleomiscosin A

CAS: 76948-72-6

Formula: C₂₀H₁₈O₈

Purity: 95%~99%

Molecular weight: 386.356

Ref: BP-SBP00604

Cleomiscosin A-d3

Controlled Product

CAS: 76948-72-6

Formula: C₂₀D₃H₁₅O₈

Color and Shape: Neat

Molecular weight: 389.371

Ref: TR-C573052

Cleomiscosin A

Controlled Product

CAS: 76948-72-6

Applications Cleomiscosin A is a known coumarinolignan and an important constituent of the methanolic extract of Hyoscyamus niger seeds (MHN) responsible for anti-inflammatory activity.
References Begum, S., et al.: Fitoterapia, 81, 178 (2010); Meena, A., et al.: Chem. Biol. Drug Des., 78, 567 (2011)

Formula: C₂₀H₁₈O₈

Color and Shape: Neat

Molecular weight: 386.35

Ref: TR-C573050