CAS 7695-70-7

Salicylic acid phenolic glucuronide

Description:

Salicylic acid phenolic glucuronide, with the CAS number 7695-70-7, is a metabolite derived from salicylic acid, a well-known plant hormone and anti-inflammatory compound. This substance is characterized by its glucuronide conjugation, which enhances its solubility and facilitates excretion from the body. It typically exhibits properties associated with phenolic compounds, including potential antioxidant activity. Salicylic acid phenolic glucuronide is often studied in the context of pharmacokinetics, as it plays a role in the metabolism of salicylic acid in humans and other organisms. Its formation is significant in understanding the therapeutic effects and side effects of salicylic acid, particularly in relation to its use in pain relief and anti-inflammatory treatments. The compound is generally stable under standard conditions but may undergo hydrolysis or other transformations in biological systems. Overall, salicylic acid phenolic glucuronide serves as an important marker in the metabolic pathways of salicylic acid and contributes to the understanding of its biological effects.

Formula: C₁₃H₁₄O₉

InChI: InChI=1S/C13H14O9/c14-7-8(15)10(12(19)20)22-13(9(7)16)21-6-4-2-1-3-5(6)11(17)18/h1-4,7-10,13-16H,(H,17,18)(H,19,20)/t7-,8-,9+,10-,13+/m0/s1

InChI key: InChIKey=JSCWDKKMLIQCMR-CDHFTJPESA-N

SMILES: O([C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O)C2=C(C(O)=O)C=CC=C2

Synonyms:

• 2-Carboxyphenyl β-D-glucopyranosiduronic acid
• Glucopyranosiduronic acid, o-carboxyphenyl, β-D-
• β-D-Glucopyranosiduronic acid, o-carboxyphenyl
• Salicyl phenolic glucuronide
• β-D-Glucopyranosiduronic acid, 2-carboxyphenyl

Salicylic Acid Phenolic β-D-Glucuronide

CAS: 7695-70-7

Formula: C₁₃H₁₄O₉

Color and Shape: White To Off-White Solid

Molecular weight: 314.25

Ref: 4Z-A-0319

1-Salicylate Glucuronide

CAS: 7695-70-7

1-Salicylate Glucuronide (Salicylic Acid b-D-O-Glucuronide) is a metabolite of salicylic acid after glucuronidation, promoting excretion.

Formula: C₁₃H₁₄O₉

Color and Shape: Solid

Molecular weight: 314.25

Ref: TM-T37484

Salicylic acid phenolic D-glucuronide

CAS: 7695-70-7

Formula: C₁₃H₁₄O₉

Purity: ≥ 95%

Color and Shape: White to off-white solid

Molecular weight: 314.24

Ref: 7W-GC2631

Salicylic acid O-β-D-glucuronide

CAS: 7695-70-7

Salicylic acid O-β-D-glucuronide

Molecular weight: 314.24486g/mol

Ref: 54-BICL2528

Salicylic Acid β-D-O-Glucuronide

Controlled Product

CAS: 7695-70-7

Applications Salicylic Acid β-D-O-Glucuronide is a metabolite of Acetylsalicylic Acid (Aspirin) (A187780).
References Grootveld, M., et al.: Biochem. Pharmacol., 37, 271 (1988), Subbegowda, R., et al.: Cancer Res., 58, 2772 (1998), Yoshida, Y., et al.: Eur. J. Pharmacol., 349, 49 (1998),

Formula: C₁₃H₁₄O₉

Color and Shape: Neat

Molecular weight: 314.24

Ref: TR-S088130

Salicylic acid D-glucuronide

CAS: 7695-70-7

Salicylic acid D-glucuronide is the major metabolite of aspirin, which is formed by hydrolysis of acetylsalicylic acid. It has been demonstrated to have anti-inflammatory and analgesic effects. Salicylic acid D-glucuronide is excreted in urine and can be detected in human serum. The formation rate of this metabolite varies with the individual's age, sex, and kidney function.
Salicylic acid D-glucuronide can be formed in vitro using hydrochloric acid and acetylsalicylic acid as substrates. This reaction is catalyzed by the enzyme uridine diphosphate glucuronyltransferase (UGT). Salicylic acid D-glucuronide has been shown to form covalent adducts with hydroxyl groups from other molecules in vivo and in vitro, including proteins (e.g., albumin) and DNA bases (e.g.,

Formula: C₁₃H₁₄O₉

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 314.24 g/mol

Ref: 3D-MS09950

Salicylic Acid B-D-O-Glucuronide-d4

Controlled Product

CAS: 7695-70-7

Formula: C₁₃D₄H₁₀O₉

Color and Shape: Neat

Molecular weight: 318.269

Ref: TR-S088132

Salicylic Acid Phenolic β-D-Glucuronide

CAS: 7695-70-7

Formula: C₁₃H₁₄O₉

Molecular weight: 314.25

Ref: ST-EA-CP-A44019