CAS 7697-26-9

3-Bromo-4-methylbenzoic acid

Description:

3-Bromo-4-methylbenzoic acid is an aromatic carboxylic acid characterized by the presence of a bromine atom and a methyl group on a benzoic acid framework. The bromine substituent is located at the meta position relative to the carboxylic acid group, while the methyl group is positioned at the para location. This compound typically appears as a white to off-white crystalline solid and is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water due to its hydrophobic aromatic structure. It exhibits typical acid properties, including the ability to donate a proton (H+) in solution, which is characteristic of carboxylic acids. The presence of the bromine atom can influence the compound's reactivity, making it useful in various organic synthesis applications, including the preparation of pharmaceuticals and agrochemicals. Additionally, its unique substitution pattern can affect its physical and chemical properties, such as melting point and reactivity in electrophilic aromatic substitution reactions. Safety precautions should be taken when handling this compound, as it may pose health risks.

Formula: C₈H₇BrO₂

InChI: InChI=1S/C8H7BrO2/c1-5-2-3-6(8(10)11)4-7(5)9/h2-4H,1H3,(H,10,11)

InChI key: InChIKey=ZFJOMUKPDWNRFI-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=CC(Br)=C(C)C=C1

Synonyms:

• 3-Bromo-4-Methylbenzoate
• 3-Bromo-4-Methylbenzoicacid
• 3-Bromo-4-methylbenzenecarboxylic acid
• 3-Bromo-p-toluic acid
• 3-Bromo-p-toluic acid (COOH=1)
• 4-Methyl -3-Bromobenzoic acid
• Benzoic acid, 3-bromo-4-methyl-
• NSC 243715
• p-Toluic acid, 3-bromo-
• 3-Bromo-4-methylbenzoic acid

3-Bromo-4-methylbenzoic Acid

CAS: 7697-26-9

Formula: C₈H₇BrO₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 215.05

Ref: 3B-B3049

3-Bromo-4-methylbenzoic acid, 98+%

CAS: 7697-26-9

3-Bromo-4-methylbenzoic acid has been used in the synthesis of biphenyl amides, 2-benzazepine-4-acetic acid derivative, as an analog of the potent, nonpeptide GPIIb/IIIa antagonist, O-spiro C-aryl glucosides. It is also used as catalytic agent and petrochemical additive. This Thermo Scientific Chem

Formula: C₈H₇BrO₂

Purity: 98+%

Color and Shape: White, Powder

Molecular weight: 215.05

Ref: 02-A11496

3-Bromo-4-Methylbenzoicacid

CAS: 7697-26-9

Formula: C₈H₇BrO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 215.0440

Ref: IN-DA003J2A

3-Bromo-4-methylbenzoic acid

CAS: 7697-26-9

3-Bromo-4-methylbenzoic acid

Formula: C₈H₇BrO₂

Purity: 98%

Color and Shape: faint orange powder

Molecular weight: 215.04g/mol

Ref: 54-OR4342

3-Bromo-4-methylbenzoic acid

CAS: 7697-26-9

Formula: C₈H₇BrO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 215.046

Ref: 10-F075171

3-Bromo-4-methylbenzoic acid

CAS: 7697-26-9

3-Bromo-4-methylbenzoic acid is a labile chemical compound that is used in the synthesis of retinoic acid, an analog of vitamin A. 3-Bromo-4-methylbenzoic acid can be synthesized by a two step process involving the boronic ester and biphenyl. The biphenyl is first treated with phosphorus pentachloride to produce a phenoxyacetate which reacts with 3-bromo-4-methylbenzoyl chloride in the presence of base to produce 3-bromo-4-methylbenzoic acid. This conversion can also be done via a solid phase synthesis where the biphenyl is anchored on silica gel and reacted with 3-bromo-4 methylbenzoyl chloride. The boronic esters are then cleaved from the solid support by treatment with sodium hydroxide under reflux conditions.
3 - Bromo -

Formula: C₈H₇BrO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 215.04 g/mol

Ref: 3D-FB45071