CAS 7698-93-3

Estradiol hemisuccinate

Description:

Estradiol hemisuccinate is a synthetic derivative of estradiol, a naturally occurring estrogen hormone. It is characterized by the addition of a hemisuccinate group, which enhances its solubility and bioavailability. This compound typically appears as a white to off-white powder and is soluble in organic solvents like ethanol and dimethyl sulfoxide, but less soluble in water. Estradiol hemisuccinate is primarily used in hormone replacement therapy and in various pharmaceutical formulations aimed at treating conditions related to estrogen deficiency. Its mechanism of action involves binding to estrogen receptors, thereby influencing gene expression and cellular activity related to reproductive and other physiological processes. The compound is also studied for its potential effects on bone density, cardiovascular health, and menopausal symptoms. Safety and efficacy profiles are essential considerations in its use, as with any hormone therapy, to mitigate risks associated with estrogen administration.

Formula: C₂₂H₂₈O₅

InChI: InChI=1/C22H28O5/c1-22-11-10-16-15-5-3-14(23)12-13(15)2-4-17(16)18(22)6-7-19(22)27-21(26)9-8-20(24)25/h3,5,12,16-19,23H,2,4,6-11H2,1H3,(H,24,25)/t16-,17-,18+,19+,22+/m1/s1

InChI key: InChIKey=YJPIDPAGJSWWBE-FNIAAEIWSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(CC[C@@H]2OC(CCC(O)=O)=O)[H]

Synonyms:

• 17beta-Estradiol hemisuccinate
• 17β-Estradiol succinate
• 4-{[(17Beta)-3-Hydroxyestra-1,3,5(10)-Trien-17-Yl]Oxy}-4-Oxobutanoic Acid
• Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 17-(hydrogen butanedioate)
• Estra-1,3,5(10)-triene-3,17-diol (17β)-, 17-(hydrogen butanedioate)
• Estra-1,3,5(10)-triene-3,17β-diol 17-(hydrogen succinate)
• Estradiol 17β-hemisuccinate
• Estradiol hemisuccinate
• Estradiol, 17-(hydrogen succinate)
• Estradiol-17-hemisuccinate
• Succinic acid, 17-monoester with estradiol
• beta-Estradiol-17-beta-hemisuccinate
• beta-Estradiol-17beta-hemisuccinate
• oestradiol 17-hemisuccinate
• 1,3,5(10)-Estratriene-3,17β-diol 17-hemisuccinate
• 1,3,5(10)-Estratriene-3,17β-diol 17-hemisuccinate, 3,17β-Hydroxy-1,3,5(10)-estratriene 17-hemisuccinate
• 17BETA-ESTRADIOL 17-HEMISUCCINATE
• β-Estradiol 17-hemisuccinate
• beta-Estradiol 17-hemisuccinate
• 17beta-estradiolhemisuccinate
• Estra-1,3,5(10)-triene-3,17b-diol 17-hemisuccinate
• 1,3,5(10)-ESTRATRIEN-3,17-BETA-DIOL 17-HEMISUCCINATE
• 3,17BETA-HYDROXY-1,3,5[10]-ESTRATRIENE 17-HEMISUCCINATE
• 3,17β-Hydroxy-1,3,5(10)-estratriene 17-hemisuccinate
• 17B-estradiol 17-hemisuccinate
• 1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 17-HEMISUCCINATE

β-Estradiol 17-hemisuccinate

CAS: 7698-93-3

Formula: C₂₂H₂₈O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 372.4547

Ref: IN-DA00579S

β-Estradiol 17-hemisuccinate

CAS: 7698-93-3

β-Estradiol 17-hemisuccinate

Purity: ≥98%

Molecular weight: 372.45g/mol

Ref: 54-BUP07627

β-Estradiol 17-hemisuccinate

CAS: 7698-93-3

Formula: C₂₂H₂₈O₅

Molecular weight: 372.45

Ref: 7W-GL0665

β-Estradiol 17-hemisuccinate

CAS: 7698-93-3

beta-Estradiol 17-hemisuccinate selectively stains estrogen receptor (ER)-rich cells.

Formula: C₂₂H₂₈O₅

Purity: 99.62%

Color and Shape: Solid

Molecular weight: 372.45

Ref: TM-T9604