CAS 77-02-1

Aprobarbital

Description:

Aprobarbital is a barbiturate derivative known for its sedative and hypnotic properties. It is classified as a central nervous system depressant and is primarily used in the medical field for its ability to induce sleep and manage anxiety. The chemical structure of aprobarbital features a barbituric acid core, which is modified to enhance its pharmacological effects. It is typically administered in oral form and has a relatively short duration of action compared to other barbiturates. Aprobarbital can cause side effects such as drowsiness, dizziness, and potential dependence with prolonged use. Its use has declined due to the availability of safer alternatives and concerns regarding abuse and overdose. As with other barbiturates, it is important to use aprobarbital under medical supervision to mitigate risks associated with its sedative effects and potential interactions with other medications. Due to its controlled status in many regions, it is subject to strict regulations regarding its prescription and distribution.

Formula: C₁₀H₁₄N₂O₃

InChI: InChI=1/C10H14N2O3/c1-4-5-10(6(2)3)7(13)11-9(15)12-8(10)14/h4,6H,1,5H2,2-3H3,(H2,11,12,13,14,15)

InChI key: InChIKey=UORJNBVJVRLXMQ-UHFFFAOYSA-N

SMILES: C(C=C)C1(C(C)C)C(=O)NC(=O)NC1=O

Synonyms:

• 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylethyl)-5-(2-propen-1-yl)-
• 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-(1-methylethyl)-5-(2-propenyl)-
• 5-(1-Methylethyl)-5-(2-propen-1-yl)-2,4,6(1H,3H,5H)-pyrimidinetrione
• 5-Ally-5-isopropyl barbituric acid
• 5-Allyl-5-isopropylbarbiturate
• 5-Allyl-5-isopropylbarbituric acid
• 5-Isopropyl-5-allylbarbituric acid
• Allional
• Allonal
• Allyisopropyl-Barbituric Acid
• Allylisopropyl-Malonylurea
• Allylisopropylbarbituric acid
• Allylisopropylmalonylurea
• Allylpropymal
• Allypropymal
• Alurate
• Alurate Elixir Verdum
• Aprobarbitone
• Aprozal
• Barbituric acid, 5-allyl-5-isopropyl-
• Isopropylallylbarbituric acid
• Nsc 120769

Aprobarbital

Controlled Product

CAS: 77-02-1

Formula: C₁₀H₁₄N₂O₃

Color and Shape: Neat

Molecular weight: 210.23

Ref: 86-MM1706.00

Aprobarbital (1 mg/ml in Methanol)

Controlled Product

CAS: 77-02-1

Formula: C₁₀H₁₄N₂O₃

Color and Shape: Single Solution

Molecular weight: 210.23

Ref: TR-KIT2295

Aprobarbital

Controlled Product

CAS: 77-02-1

Applications Controlled substance (depressant). Sedative, hypnotic.
References Frey, H.H., et al.: Arzneim. Forsch., 12, 389 (1962), Turner, J., et al.: Pharm. Res., 21, 68 (2004), Votano, J., et al.: J. Med. Chem., 49, 7169 (2006),

Formula: C₁₀H₁₄N₂O₃

Color and Shape: Neat

Molecular weight: 210.23

Ref: TR-A735400