CAS 77-17-8

Normeperidine

Description:

Normeperidine is a chemical compound that serves as a metabolite of the opioid analgesic meperidine. It is classified as a piperidine derivative and is known for its analgesic properties, although it is less potent than its parent compound. Normeperidine is characterized by its ability to cross the blood-brain barrier, which contributes to its central nervous system effects. The compound has a relatively long half-life compared to meperidine, leading to potential accumulation in patients with renal impairment. This accumulation can result in neurotoxic effects, such as seizures, particularly with prolonged use or high doses. Normeperidine is typically not used therapeutically on its own but is important in understanding the pharmacokinetics and safety profile of meperidine. Its chemical structure includes a piperidine ring, and it is soluble in organic solvents. Due to its potential side effects, careful monitoring is advised when meperidine is administered, especially in vulnerable populations.

Formula: C₁₄H₁₉NO₂

InChI: InChI=1S/C14H19NO2/c1-2-17-13(16)14(8-10-15-11-9-14)12-6-4-3-5-7-12/h3-7,15H,2,8-11H2,1H3

InChI key: InChIKey=QKHMFBKXTNQCTM-UHFFFAOYSA-N

SMILES: C(OCC)(=O)C1(CCNCC1)C2=CC=CC=C2

Synonyms:

• 4-(Ethoxycarbonyl)-4-phenylpiperidine
• 4-Carbethoxy-4-phenylpiperidine
• 4-Phenyl-4-carbethoxypiperidine
• 4-Phenylpiperidine-4-carboxylic acid ethyl ester
• 4-Piperidinecarboxylic acid, 4-phenyl-, ethyl ester
• Ethyl 4-phenylisonipecotate
• Isonipecotic acid, 4-phenyl-, ethyl ester
• N-Desmethylmeperidine
• NSC 23821
• Nordolsin
• Normeperidine

Pethidine EP Impurity E

Controlled Product

CAS: 77-17-8

Formula: C₁₄H₁₉NO₂

Color and Shape: Neat

Molecular weight: 233.31

Ref: 86-MM0315.05

Norpethidine (Normeperidine)

Controlled Product

CAS: 77-17-8

Color and Shape: Neat

Ref: 61-FOR0315.05

Ethyl 4-Phenylpiperidine-4-carboxylate

Controlled Product

CAS: 77-17-8

Formula: C₁₄H₁₉NO₂

Color and Shape: Neat

Molecular weight: 233.31

Ref: TR-E940938