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CAS 77-21-4

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(±)-Glutethimide

Description:
(±)-Glutethimide is a synthetic compound primarily used as a sedative and hypnotic agent. It belongs to the class of drugs known as imides and is characterized by its ability to depress the central nervous system, leading to effects such as sedation and sleep induction. The molecular formula of (±)-Glutethimide is C12H15N, and it features a unique structure that includes a glutamic acid derivative. This compound is typically encountered as a white to off-white crystalline powder, which is soluble in organic solvents but has limited solubility in water. Its pharmacological effects are attributed to its interaction with GABA receptors, enhancing the inhibitory neurotransmitter's action. While it has therapeutic applications, (±)-Glutethimide also carries the potential for abuse and dependence, necessitating careful monitoring when prescribed. Due to its sedative properties, it is important to consider potential side effects, including drowsiness, dizziness, and impaired coordination. As with any medication, proper dosage and adherence to medical guidance are crucial for safe use.
Formula:C13H15NO2
InChI:InChI=1/C13H15NO2/c1-2-13(10-6-4-3-5-7-10)9-8-11(15)14-12(13)16/h3-7H,2,8-9H2,1H3,(H,14,15,16)
InChI key:InChIKey=JMBQKKAJIKAWKF-UHFFFAOYSA-N
SMILES:C(C)C1(C(=O)NC(=O)CC1)C2=CC=CC=C2
Synonyms:
  • (.+-.)-2-Ethyl-2-phenylglutarimide
  • (.+-.)-3-Ethyl-3-phenyl-2,6-piperidinedione
  • (.+-.)-Glutethimide
  • 2-Phenyl-2-ethylglutaric acid imide
  • 3-Ethyl-3-phenyl-2,6-diketopiperidine
  • 3-Ethyl-3-phenyl-2,6-dioxopiperidine
  • 3-Ethyl-3-phenylglutarimide
  • 3-Phenyl-3-ethyl-2,6-diketopiperidine
  • 3-Phenyl-3-ethyl-2,6-dioxopiperidine
  • Doriden
  • See more synonyms
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  • Glutethimide
    TRC
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    Glutethimide

    Controlled Product
    CAS:

    Applications rac-Glutethimide is a hypnotic sedative which was once used to treat insomnia. When taken with codeine, it has an intense euphoric effect on the subject due to the body’s increased ability to convert codeine to morphine.
    References Popa, D., et al.: J. Pharmaceut. Biomed., 32, 867 (2002);

    Formula:C13H15NO2
    Color and Shape:White
    Molecular weight:217.26

    Ref: TR-G598150

    10mg
    124.00€
    100mg
    350.00€