CAS 77-37-2

(±)-Procyclidine

Description:

(±)-Procyclidine is a synthetic anticholinergic agent primarily used in the treatment of Parkinson's disease and drug-induced extrapyramidal symptoms. It functions by blocking the action of acetylcholine at muscarinic receptors, thereby alleviating symptoms such as rigidity and tremors. This compound is characterized by its chiral nature, existing as a racemic mixture of two enantiomers, which can exhibit different pharmacological effects. Procyclidine is typically administered orally and is known for its relatively rapid onset of action. In terms of physical properties, it is a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. Side effects may include dry mouth, blurred vision, and constipation, which are common to anticholinergic medications. Due to its mechanism of action, procyclidine is also studied for its potential effects on cognitive function and its role in managing other conditions associated with cholinergic dysfunction. As with any medication, it is essential to use procyclidine under medical supervision to manage dosage and monitor for adverse effects.

Formula: C₁₉H₂₉NO

InChI: InChI=1S/C19H29NO/c21-19(17-9-3-1-4-10-17,18-11-5-2-6-12-18)13-16-20-14-7-8-15-20/h1,3-4,9-10,18,21H,2,5-8,11-16H2

InChI key: InChIKey=WYDUSKDSKCASEF-UHFFFAOYSA-N

SMILES: C(CCN1CCCC1)(O)(C2CCCCC2)C3=CC=CC=C3

Synonyms:

• (.+-.)-Procyclidine
• 1-Cyclohexyl-1-phenyl-3-(1-pyrrolidinyl)-1-propanol
• 1-Cyclohexyl-1-phenyl-3-pyrrolidinopropan-1-ol
• Elorine
• Kemadrine
• Lergine
• Nsc 169103
• Prociclidina
• Procyclidin
• Tricoloid
• Tricyclamol
• Vagosin
• α-Cyclohexyl-α-phenyl-1-pyrrolidinepropanol
• 1-Pyrrolidinepropanol, α-cyclohexyl-α-phenyl-

Procyclidine

CAS: 77-37-2

Procyclidine is an anticholinergic, muscarinic and NMDA antagonist used in Parkinson's and psychiatric disorder studies.

Formula: C₁₉H₂₉NO

Color and Shape: Solid

Molecular weight: 287.44

Ref: TM-T60578