CAS 77-86-1

Tris(hydroxymethyl)aminomethane

Description:

Tris(hydroxymethyl)aminomethane, commonly known as Tris, is an organic compound with the chemical formula C4H11NO3. It is a white crystalline solid that is highly soluble in water, making it an effective buffering agent in biochemical and molecular biology applications. Tris has a pKa value around 8.1, which allows it to maintain a stable pH in biological systems, particularly in the physiological range. It is often used in the preparation of buffer solutions for electrophoresis and other laboratory techniques. Tris is non-toxic and has low volatility, which contributes to its widespread use in research settings. Additionally, it can form stable complexes with metal ions, which can be advantageous in various biochemical assays. However, it is important to note that Tris can interfere with certain assays, particularly those involving phenolic compounds. Overall, Tris is a versatile and essential reagent in many scientific fields, particularly in biochemistry and molecular biology.

Formula: C₄H₁₁NO₃

InChI: InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key: InChIKey=LENZDBCJOHFCAS-UHFFFAOYSA-N

SMILES: C(CO)(CO)(CO)N

Synonyms:

• 1,3-Dihydroxy-2-(hydroxymethyl)propan-2-amine
• 2-Amino-1,3-dihydroxy-2-(hydroxymethyl)propane
• 2-Amino-2-(Hydroxymethyl)-1,3-Propandiol
• 2-Amino-2-(hydroxymethyl)-1,3-propanediol
• 2-Amino-2-(hydroxymethyl)propane-1,3-diol
• 2-Amino-2-(hydroxymethyl)propanediol
• 2-Amino-2-hydroxymethyl-1, 3-propanediol
• 2-Amino-2-hydroxymethylpropan-1,3-diol
• 2-Amino-2-methylol-1,3-propanediol
• A 0321
• Addex-Tham
• Aminomethane
• Aminotri(hydroxymethyl)methane
• Aminotrimethylolmethane
• Aminotris(hydroxymethyl)methane
• Methanamine, 1,1,1-tris(hydroxymethyl)-
• Nsc 103026
• Nsc 6365
• Nsc 65434
• Pehanorm
• Propane-1,3-Diol, 2-Amino-2-(Hydroxymethyl)-
• Ricrolin TE
• Sarkosyl
• T 1503
• TAM
• TAM (buffering agent)
• Talatrol
• Tham
• Toris Amino Ultra PC
• Tri Amino
• Tri(hydroxymethyl)aminomethane
• Tri(hydroxymethyl)methylamine
• Trigmo base
• Trihydroxymethylaminomethane (Tham)
• Triladyl
• Trimethylolaminomethane
• Tris
• Tris (Base)
• Tris (buffering agent)
• Tris Amino
• Tris Amino Crystal
• Tris Amino Ultra
• Tris Amino Ultra PC (J) tromethamine
• Tris Buffer
• Tris(Hydroxymethyl)Methylamine
• Tris(hydroxymethyl)aminomethane
• Tris(hydroxymethyl)methanamine
• Tris(methylolamino)methane
• Tris, free base
• Tris-steril
• Trisamin
• Trisamine
• Trisaminol
• Trishydroxymethylaminomethane
• Trispuffer
• Trizma
• Trizma Base
• Trometamol
• Trometamole
• Tromethamine
• Tromethane
• Tromethanmin
• Tutofusin tris
• [2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]amine

Tris(hydroxymethyl)aminomethane

Controlled Product

CAS: 77-86-1

Formula: C₄H₁₁NO₃

Purity: >99.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 121.14

Ref: 3B-A0321

Tris(hydroxymethyl)aminomethane [for Electrophoresis]

Controlled Product

CAS: 77-86-1

Formula: C₄H₁₁NO₃

Purity: >99.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 121.14

Ref: 3B-T2516

Tris(hydroxymethyl)aminomethane, Electrophoresis Grade, 99.9%

Controlled Product

CAS: 77-86-1

Used as a biological buffer substance in the pH range 79; pKa = 8.3 at 20C; pKa = 7.82 at 37C. Used as a biological buffer or as a component of buffer formulations such as TAE and TBE buffers. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capa

Formula: C₄H₁₁NO₃

Purity: 99.9%

Color and Shape: White, Powder or crystals or crystalline powder

Molecular weight: 121.14

Ref: 02-J62569

TRIS, 1.0M buffer soln., pH 6.8

Controlled Product

CAS: 77-86-1

A compound widely used as a biological buffer substance. It is widely used as a biological buffer or as a component of buffer formulations such as TAE and TBE buffers. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of

Ref: 02-J63831

Tris(hydroxymethyl)aminomethane, ultrapure, 99.9%

Controlled Product

CAS: 77-86-1

Tris(hydroxymethyl)aminomethane is used as buffers in biochemistry and molecular biology laboratories. It is used as a primary standard to standardize acid solutions for chemical analysis. It finds application in cell membranes to increase its permeability. As an alternative to sodium bicarbonate, i

Formula: C₄H₁₁NO₃

Purity: 99.9%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 121.14

Ref: 02-J65594

TRIS, 0.5M buffer soln., pH 8.5

Controlled Product

CAS: 77-86-1

TRIS, 1.0M buffer soln., pH 7.5 is used as buffers for stabilizing and storing nucleic acids and proteins. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alf

Ref: 02-J62131

TRIS, 1.0M buffer soln., pH 8.4

Controlled Product

CAS: 77-86-1

Used as a biological buffer substance in the pH range 79; pKa = 8.3 at 20C; pKa = 7.82 at 37C. Used as a biological buffer or as a component of buffer formulations such as TAE and TBE buffers. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capa

Formula: C₄H₁₁NO₃

Color and Shape: Liquid, Clear, colorless

Molecular weight: 121.14

Ref: 02-J62577

TRIS, 1.0M buffer soln., pH 7.5

Controlled Product

CAS: 77-86-1

TRIS, 1.0M buffer soln., pH 7.5 is used as buffers for stabilizing and storing nucleic acids and proteins. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alf

Ref: 02-J60636

THAM, ≥99.5%

Controlled Product

CAS: 77-86-1

Purity: ≥99.5%

Molecular weight: 121.07

Ref: 10-F569066

TRIS, 1.0M buffer soln., pH 7.0

Controlled Product

CAS: 77-86-1

Used as a biological buffer substance in the pH range 79; pKa = 8.3 at 20C; pKa = 7.82 at 37C. Used as a biological buffer or as a component of buffer formulations such as TAE and TBE buffers. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capa

Ref: 02-J62657

TRIS, 0.5M buffer soln., pH 6.8

Controlled Product

CAS: 77-86-1

TRIS is used as a standard biological buffer in less critical applications where economy is an important consideration, component of extraction buffer e.g. phenol extraction of DNA or RNA; and as a component of separating and stacking gels in the characterization of in vitro translation products by

Ref: 02-J63735

TRIS, 1.0M buffer soln., pH 8.0

Controlled Product

CAS: 77-86-1

Used as a biological buffer substance in the pH range 79; pKa = 8.3 at 20C; pKa = 7.82 at 37C. Used as a biological buffer or as a component of buffer formulations such as TAE and TBE buffers. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capa

Ref: 02-J62726

TRIS, 1.0M buffer soln., pH 7.6

Controlled Product

CAS: 77-86-1

TRIS, 1.0M buffer soln., pH 7.5 is used as buffers for stabilizing and storing nucleic acids and proteins. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alf

Ref: 02-J61036

TRIS-buffered saline (TBS, 10X, high salt) pH 7.4

Controlled Product

CAS: 77-86-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Ref: 02-J62664

TRIS, 1.0M buffer soln., pH 8.2

Controlled Product

CAS: 77-86-1

TRIS, 1.0M buffer soln., pH 7.5 is used as buffers for stabilizing and storing nucleic acids and proteins. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alf

Ref: 02-J61798

Tris(hydroxymethyl)aminomethane, ACS, 99.8-100.1% (Assay, dried basis)

Controlled Product

CAS: 77-86-1

Tris(hydroxymethyl)aminomethane is used as a buffer in biochemistry and molecular biology laboratories. It is used as a primary standard to standardize acid solutions for chemical analysis. It finds application in cell membranes to increase permeability. As an alternative to sodium bicarbonate, it u

Formula: C₄H₁₁NO₃

Purity: 99.8-100.1%

Molecular weight: 121.14

Ref: 02-031801

TRIS-buffered saline (TBS, 20X) pH 7.4

Controlled Product

CAS: 77-86-1

Tris Buffered Saline (TBS) is a pH stabilizing solution used for western blot and ELISA procedures. It is used as a convenient prepared buffer for use in various applications. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation a

Formula: C₄H₁₁NO₃

Color and Shape: Clear colorless, Liquid

Molecular weight: 121.14

Ref: 02-J60877

TRIS, 1.0M buffer soln., pH 7.5, 0.2 micron filtered

Controlled Product

CAS: 77-86-1

Tris Buffered Saline (TBS) is a pH stabilizing solution used for western blot and ELISA procedures. It is used as a convenient prepared buffer for use in various applications. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation a

Ref: 02-J62993

TRIS, 1.0M buffer soln., pH 8.5, 0.2 micron filtered

Controlled Product

CAS: 77-86-1

TRIS, 1.0M buffer soln., pH 8.5 is used as buffers for stabilizing and storing nucleic acids and proteins. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alf

Formula: C₄H₁₁NO₃

Color and Shape: Clear liquid

Molecular weight: 121.14

Ref: 02-J61038

Tris, ≥98%

Controlled Product

CAS: 77-86-1

Thermo Scientific Tris Ultrapure

Formula: C₄H₁₁NO₃

Purity: 98%

Color and Shape: White to pale yellow crystalline powder

Molecular weight: 121.14

Ref: 02-J22675

TRIS, 1.0M buffer soln., pH 9.5

Controlled Product

CAS: 77-86-1

TRIS, 1.0M buffer soln., pH 9.5 is used as buffers for stabilizing and storing nucleic acids and proteins. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alf

Ref: 02-J62084

Tris, 99.0 to 101.0% (Dry Basis)

Controlled Product

CAS: 77-86-1

Thermo Scientific Tris Molecular Biology Grade

Formula: C₄H₁₁NO₃

Purity: 101.0%

Color and Shape: White/clear crystalline powder

Molecular weight: 121.14

Ref: 02-J22674

Tris(hydroxymethyl)aminomethane, 99%

Controlled Product

CAS: 77-86-1

Tris(hydroxymethyl)aminomethane is used as buffers in biochemistry and molecular biology laboratories. It is used as a primary standard to standardize acid solutions for chemical analysis. It finds application in cell membranes to increase its permeability. As an alternative to sodium bicarbonate,

Formula: C₄H₁₁NO₃

Purity: 99%

Color and Shape: White, Crystalline powder or crystals and/or chunks

Molecular weight: 121.14

Ref: 02-A18494

TRIS-buffered saline (TBS, 10X) pH 7.4, for Western blot

Controlled Product

CAS: 77-86-1

For Western blot washing

Formula: C₄H₁₁NO₃

Color and Shape: Clear colorless, Liquid

Molecular weight: 121.14

Ref: 02-J62938

Tris(hydroxymethyl)aminomethane, Molecular Biology Grade, 99.9%

Controlled Product

CAS: 77-86-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₁₁NO₃

Purity: 99.9%

Molecular weight: 121.14

Ref: 02-J61062

TRIS, 1.0M buffer soln., pH 9.0, 0.2 micron filtered

Controlled Product

CAS: 77-86-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Ref: 02-J60707

TRIS-buffered saline (TBS, 10X) pH 8.0

Controlled Product

CAS: 77-86-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Ref: 02-J62780

TRIS, 1.0M buffer soln., pH 7.2

Controlled Product

CAS: 77-86-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Ref: 02-J62186

TRIS, 1.0M buffer soln., pH 8.0, 0.2 micron filtered

Controlled Product

CAS: 77-86-1

TRIS, 1.0M buffer soln., pH 7.5 is used as buffers for stabilizing and storing nucleic acids and proteins. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alf

Ref: 02-J61429

TRIS, 0.5M buffer soln., pH 7.5

Controlled Product

CAS: 77-86-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Ref: 02-J61141

TRIS, 1.0M buffer soln., pH 7.4

Controlled Product

CAS: 77-86-1

Tris is used in pH control in buffering systems for electrophoresis applications.Tris is used in assays used to characterize the activity and kinetics of the enzymes that catalyze SUMOylation of Small ubiquitin-like proteins (SUMO) and SUMO-dependent protein-protein interactions. Also used as buffer

Ref: 02-J60202

TRIS, 1.0M buffer soln., pH 6.5, 0.2 micron filtered

Controlled Product

CAS: 77-86-1

TRIS, 1.0M buffer soln., pH 7.5 is used as buffers for stabilizing and storing nucleic acids and proteins. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alf

Ref: 02-J62264

Tris, 99.8 to 100.1% (Dry Basis), Molecular Biology Grade, Ultrapure

Controlled Product

CAS: 77-86-1

Thermo Scientific Tris Molecular Biology Grade Ultrapure

Formula: C₄H₁₁NO₃

Purity: 100.1%

Color and Shape: White crystalline powder

Molecular weight: 121.14

Ref: 02-J75825

Tris(hydroxymethyl)aminomethane, Electrophoresis Grade, 99.5%

Controlled Product

CAS: 77-86-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₁₁NO₃

Purity: 99.5%

Molecular weight: 121.14

Ref: 02-J61016

TRIS-buffered saline (TBS, 10X) pH 7.6

Controlled Product

CAS: 77-86-1

TRIS-buffered saline (TBS, 10X) pH 7.6 is used as a substance diluent, as a wash buffer in immunoassays such as enzyme-linked immunosorbent assay. It is used in antibody diluent in western blotting, sample diluent in vitro diagnostics, immuno-histochemical staining and in situ hybridization. This Th

Ref: 02-J62662

TRIS, 0.5M buffer soln., pH 8.8

Controlled Product

CAS: 77-86-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₁₁NO₃

Color and Shape: Clear liquid

Molecular weight: 121.14

Ref: 02-J61144

TRIS, 1.0M buffer soln., pH 7.8

Controlled Product

CAS: 77-86-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Ref: 02-J61579

TRIS, 1.0M buffer soln., pH 8.8

Controlled Product

CAS: 77-86-1

TRIS, 1.0M buffer is used as buffers for stabilizing and storing nucleic acids and proteins. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar produc

Formula: C₄H₁₁NO₃

Color and Shape: Clear liquid

Molecular weight: 121.14

Ref: 02-J60452

TRIS, 1.0M buffer soln., pH 6.5

Controlled Product

CAS: 77-86-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Ref: 02-J60381

TROMETAMOL CRS

Controlled Product

CAS: 77-86-1

TROMETAMOL CRS

Formula: C₄H₁₁NO₃

Color and Shape: Crystalline Powder. White. Colourless Crystals. Powder.

Molecular weight: 121.135

Ref: 41-T2550000

Tromethamine

Controlled Product

CAS: 77-86-1

Amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters, salts thereof, nesoi

Formula: C₄H₁₁NO₃

Color and Shape: White Powder

Molecular weight: 121.07389

Ref: 45-1698002

2-Amino-2-(hydroxymethyl)-1,3-propanediol

Controlled Product

CAS: 77-86-1

Formula: C₄H₁₁NO₃

Purity: %

Color and Shape: Solid

Molecular weight: 121.1350

Ref: IN-DA00397K

Trometamol

Controlled Product

CAS: 77-86-1

Trometamol: treats acidemia, blocks COX1/COX2, inhibits pro-inflammatory prostaglandins.

Formula: C₄H₁₁NO₃

Purity: 99.05% - 99.88%

Color and Shape: White Solid Crystalline

Molecular weight: 121.14

Ref: TM-T0961

AVIPure® Sample Diluent

Controlled Product

CAS: 77-86-1

Sample diluent recommended for sample dilutions in the Avitide AVIPure® – AAV9 Residual Ligand Assay (F970).

Ref: 5M-I300

TRIS solution, 20mM in water, pH 8

Controlled Product

CAS: 77-86-1

Formula: C₄H₁₁NO₃

Color and Shape: Clear, colourless liquid

Molecular weight: 121.14

Ref: 7W-GP1622

TRIS solution, 10mM in water, pH 8

Controlled Product

CAS: 77-86-1

Formula: C₄H₁₁NO₃

Color and Shape: Clear, colourless liquid

Molecular weight: 121.14

Ref: 7W-GP3421

TRIS Ultrapure, 99.9%, Ph. Eur. grade

Controlled Product

CAS: 77-86-1

Formula: C₄H₁₁NO₃

Purity: (Titration) 99.90 - 100.50 % (dried substance)

Color and Shape: White crystalline powder or colourless crystals

Molecular weight: 121.14

Ref: 7W-GB1923

TRIS solution, 50mM in water, pH 8

Controlled Product

CAS: 77-86-1

Formula: C₄H₁₁NO₃

Color and Shape: Clear, colourless liquid

Molecular weight: 121.14

Ref: 7W-GP1147

TRIS

Controlled Product

CAS: 77-86-1

Formula: C₄H₁₁NO₃

Purity: ≥ 99.0% (anhydrous)

Color and Shape: White crystalline powder or crystals

Molecular weight: 121.14

Ref: 7W-GP7166

TRIS solution, 1M in water, pH 9

Controlled Product

CAS: 77-86-1

Formula: C₄H₁₁NO₃

Color and Shape: Clear, colourless liquid

Molecular weight: 121.14

Ref: 7W-GP6989