CAS 77-86-1: Tris(hydroxymethyl)aminomethane

Description:Tris(hydroxymethyl)aminomethane, commonly known as Tris, is an organic compound with the chemical formula C4H11NO3. It is a white crystalline solid that is highly soluble in water, making it an effective buffering agent in biochemical and molecular biology applications. Tris has a pKa value around 8.1, which allows it to maintain a stable pH in biological systems, particularly in the physiological range. It is often used in the preparation of buffer solutions for electrophoresis and other laboratory techniques. Tris is non-toxic and has low volatility, which contributes to its widespread use in research settings. Additionally, it can form stable complexes with metal ions, which can be advantageous in various biochemical assays. However, it is important to note that Tris can interfere with certain assays, particularly those involving phenolic compounds. Overall, Tris is a versatile and essential reagent in many scientific fields, particularly in biochemistry and molecular biology.

Formula:C₄H₁₁NO₃

InChI:InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

InChI key:InChIKey=LENZDBCJOHFCAS-UHFFFAOYSA-N

SMILES:OCC(N)(CO)CO

Synonyms:
1,3-Dihydroxy-2-(hydroxymethyl)propan-2-amine
2-Amino-1,3-dihydroxy-2-(hydroxymethyl)propane
2-Amino-2-(Hydroxymethyl)-1,3-Propandiol
2-Amino-2-(hydroxymethyl)-1,3-propanediol
2-Amino-2-(hydroxymethyl)propane-1,3-diol
2-Amino-2-(hydroxymethyl)propanediol
2-Amino-2-hydroxymethyl-1, 3-propanediol
2-Amino-2-hydroxymethylpropan-1,3-diol
2-Amino-2-methylol-1,3-propanediol
A 0321
See more synonyms
Addex-Tham
Aminomethane
Aminotri(hydroxymethyl)methane
Aminotrimethylolmethane
Aminotris(hydroxymethyl)methane
Methanamine, 1,1,1-tris(hydroxymethyl)-
Nsc 103026
Nsc 6365
Nsc 65434
Pehanorm
Propane-1,3-Diol, 2-Amino-2-(Hydroxymethyl)-
Ricrolin TE
Sarkosyl
T 1503
TAM
TAM (buffering agent)
Talatrol
Tham
Toris Amino Ultra PC
Tri Amino
Tri(hydroxymethyl)aminomethane
Tri(hydroxymethyl)methylamine
Trigmo base
Trihydroxymethylaminomethane (Tham)
Triladyl
Trimethylolaminomethane
Tris
Tris (Base)
Tris (buffering agent)
Tris Amino
Tris Amino Crystal
Tris Amino Ultra
Tris Amino Ultra PC (J) tromethamine
Tris Buffer
Tris(Hydroxymethyl)Methylamine
Tris(hydroxymethyl)aminomethane
Tris(hydroxymethyl)methanamine
Tris(methylolamino)methane
Tris, free base
Tris-steril
Trisamin
Trisamine
Trisaminol
Trishydroxymethylaminomethane
Trispuffer
Trizma
Trizma Base
Trometamol
Trometamole
Tromethamine
Tromethane
Tromethanmin
Tutofusin tris
[2-Hydroxy-1,1-bis(hydroxymethyl)ethyl]amine
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

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Product data	Purity	Price range	Estimated delivery
Trometamol REF: 86-MM1566.00CAS: 77-86-1	- - -	324.00 €	Wed 30 Apr 25
Trometamol REF: 4Z-T-296001CAS: 77-86-1	- - -	To inquire	Tue 06 May 25
TRIS (USP, BP, Ph. Eur.) pure REF: 54-BIA141940CAS: 77-86-1	Pharma Grade	143.00 €	Tue 06 May 25
Tromethamine REF: TR-T892600CAS: 77-86-1	- - -	88.00 €~200.00 €	Wed 07 May 25
Tris REF: 3D-FT15751CAS: 77-86-1	- - -	148.00 €~2,416.00 €	Thu 08 May 25
Tris Buffer Superior for molecular biology, 99.9% REF: SR-37969CAS: 77-86-1	min. 99.9%(By neutralization)	26.00 €~538.00 €	Tue 27 May 25
Tris Buffer for HPLC, 99.9% REF: SR-56995CAS: 77-86-1	min. 99.9%(By neutralization)	36.00 €~80.00 €	Tue 27 May 25
Tris Buffer AR, ACS for molecular biology, 99.9% REF: SR-71033CAS: 77-86-1	min. 99.9%(By neutralization)	21.00 €~420.00 €	Tue 27 May 25
Tris Buffer Superior extrapure AR, ACS, 99.9% REF: SR-79420CAS: 77-86-1	min. 99.9%(By neutralization)	24.00 €~472.00 €	Tue 27 May 25
Tris Buffer USP, 99-101% (Non Injectable Use) REF: SR-16622CAS: 77-86-1	99 - 101%	97.00 €~451.00 €	Tue 27 May 25
Tris Buffer for cell culture, 99.9%, Endotoxin (BET) 0.05 EU/mg REF: SR-12695CAS: 77-86-1	min. 99.9%	32.00 €~71.00 €	Tue 27 May 25