CAS 770-12-7

Phosphorodichloridic acid, phenyl ester

Description:

Phosphorodichloridic acid, phenyl ester, also known as phenyl dichlorophosphate, is an organophosphorus compound characterized by its phosphorus atom bonded to two chlorine atoms and one phenyl group. This compound typically appears as a colorless to pale yellow liquid with a pungent odor. It is known for its reactivity, particularly as a phosphorus-containing reagent in organic synthesis and as an intermediate in the production of various chemicals. The presence of chlorine atoms makes it a potential source of chlorinated derivatives, while the phenyl group contributes to its aromatic properties. Phosphorodichloridic acid, phenyl ester is sensitive to moisture and can hydrolyze in the presence of water, releasing hydrochloric acid and forming phosphoric acid derivatives. Due to its chemical properties, it is important to handle this compound with care, as it can be corrosive and toxic. Proper safety measures, including the use of personal protective equipment, are essential when working with this substance in laboratory or industrial settings.

Formula: C₆H₅Cl₂O₂P

InChI: InChI=1/C6H5Cl2O2P/c7-11(8,9)10-6-4-2-1-3-5-6/h1-5H

InChI key: InChIKey=TXFOLHZMICYNRM-UHFFFAOYSA-N

SMILES: O(P(Cl)(Cl)=O)C1=CC=CC=C1

Synonyms:

• Dichlorophenoxyphosphine oxide
• Dichlorophosphoric Acid Phenyl Ester
• Monophenyl dichlorophsphate
• Mpcp
• NSC 44412
• Phenoxydichlorophosphine oxide
• Phenoxyphosphoryl dichloride
• Phenyl dichlorophosphinate
• Phenyl phosphorodichloridate
• Phenylphosphoric dichloride
• Phosphoric Acid Phenyl Ester Dichloride
• Phosphorodichloridic acid, phenyl ester
• Phenyl dichlorophosphate
• PHENYLPHOSPHORYL DICHLORIDE
• PHENYL PHOSPHODICHLORIDATE
• Phosphoro-dichloridicacid,phenylester
• Phenyl dichloridophosphate
• dichlorophenoxyphosphineoxide
• phenoxyphosphoryldichloride
• phenylphosphoricdichloride
• Phenyl phosphorodichlorodate
• phenoxydichlorophosphineoxide
• phosphorodichloridicacid,phenylester

Phenyl Dichlorophosphate

CAS: 770-12-7

Formula: C₆H₅Cl₂O₂P

Purity: >98.0%(T)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 210.98

Ref: 3B-P0209

Phenyl phosphorodichloridate, 97%

CAS: 770-12-7

Reagent for preparation of phosphate diesters.Phenyl phosphorodichloridate is used in the preparation of symmetrical phosphate diesters. It is used as a phosphorylating agent for alcohols and amines. It is also involved in the preparation of phenylphosphoro di-(1-imidazolidate) and 2-phenyl-bis-tria

Formula: C₆H₅Cl₂O₂P

Purity: 97%

Color and Shape: Clear colorless to pale yellow, Liquid

Molecular weight: 210.98

Ref: 02-A10479

Phenyl Phosphorodichloridate

CAS: 770-12-7

Formula: C₆H₅Cl₂O₂P

Purity: 97%

Color and Shape: Liquid

Molecular weight: 210.9825

Ref: IN-DA0035H0

Phenyl dichlorophosphate

CAS: 770-12-7

Phenyl dichlorophosphate

Formula: C₆H₅Cl₂O₂P

Purity: 97%

Color and Shape: clear. colourless liquid

Molecular weight: 210.98g/mol

Ref: 54-OR10815

Phenyl phosphorodichloridate

CAS: 770-12-7

Formula: C₆H₅Cl₂O₂P

Purity: 97%

Color and Shape: Liquid, Clear

Molecular weight: 210.98

Ref: 10-F095121

Phenyl Dichlorophosphate

Controlled Product

CAS: 770-12-7

Stability Moisture Sensitive
Applications Phenyl Dichlorophosphate is used as a reagent in the synthesis of aspartic acid based nucleoside phosphoramidate prodrugs as potent inhibitors of hepatitis C virus replication. Also a reagent in the synthesis of nucleotide prodrugs of 2'-deoxy-2'-spirooxetane ribonucleosides as inhibitors of HCV NS5B polymerase.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Maiti, M., et al.: Org. Biomol. Chem., 13, 5158 (2015); Jonckers, T.H.M., et al.: J. Med. Chem., 57, 1836 (2014)

Formula: C₆H₅Cl₂O₂P

Color and Shape: Neat

Molecular weight: 210.98

Ref: TR-P319950