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CAS 77128-73-5

:

fmoc-N-methyl-L-phenylalanine

Description:
Fmoc-N-methyl-L-phenylalanine, with the CAS number 77128-73-5, is a derivative of the amino acid phenylalanine, modified with a fluorenylmethyloxycarbonyl (Fmoc) protecting group on the amino group and a methyl group on the nitrogen atom. This compound is characterized by its role in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS), where the Fmoc group serves as a protective group that can be easily removed under basic conditions. The presence of the N-methyl group enhances the compound's lipophilicity and can influence the conformation and stability of peptides. Fmoc-N-methyl-L-phenylalanine is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its structural features contribute to its utility in the development of peptide-based drugs and in various biochemical applications, including studies of protein interactions and structure-function relationships.
Formula:C25H23NO4
Synonyms:
  • Fmoc-N-Me-Phe-OH
  • N-alpha-(9-fluorenylmethyloxycarbonyl)-N-alpha-Methyl-L-phenylalanine
  • FMOC-N-ALPHA-METHYL-L-PHENYLALANINE
  • N-ALPHA-FMOC-N-ALPHA-METHYL-L-PHENYLALANINE
  • FMOC-L-MEPHE-OH
  • FMOC-N-METHYL-L-PHENYLALANINE LIQUID
  • FMOC-MEPHE-OH
  • FMOC-N-METHYL-L-PHENYLALANINE
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-ALPHA-METHYL-L-PHENYLALANINE
  • FMOC-N-ME-PHENYLALANINE
  • See more synonyms
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