CAS 77164-20-6

(-)-Moprolol

Description:

(-)-Moprolol is a beta-blocker medication primarily used in the treatment of hypertension and certain heart conditions. It is characterized by its selective antagonism of beta-adrenergic receptors, which helps to reduce heart rate and myocardial contractility, ultimately lowering blood pressure. The compound is a chiral molecule, with the "(-)" designation indicating its specific enantiomeric form, which is biologically active. Its chemical structure includes a phenolic ring and an aliphatic side chain, contributing to its pharmacological properties. (-)-Moprolol is typically administered orally and is known for its relatively favorable side effect profile compared to non-selective beta-blockers. Additionally, it has a moderate lipophilicity, allowing for effective absorption and distribution in the body. As with other beta-blockers, caution is advised in patients with asthma or certain cardiovascular conditions, as it may exacerbate bronchospasm or lead to bradycardia. Overall, (-)-Moprolol plays a significant role in cardiovascular therapy, demonstrating the importance of beta-adrenergic modulation in clinical practice.

Formula: C₁₃H₂₁NO₃

InChI: InChI=1S/C13H21NO3/c1-10(2)14-8-11(15)9-17-13-7-5-4-6-12(13)16-3/h4-7,10-11,14-15H,8-9H2,1-3H3/t11-/m0/s1

InChI key: InChIKey=LFTFGCDECFPSQD-NSHDSACASA-N

SMILES: O(C[C@H](CNC(C)C)O)C1=C(OC)C=CC=C1

Synonyms:

• (-)-(S)-1-(Isopropylamino)-3-(o-methoxyphenoxy)-2-propanol
• (-)-Moprolol
• (2S)-1-(2-Methoxyphenoxy)-3-[(1-methylethyl)amino]-2-propanol
• (2S)-1-(2-methoxyphenoxy)-3-[(1-methylethyl)amino]propan-2-ol
• (S)-1-(2-Methoxyphenoxy)-3-((1-methylethyl)amino)-2-propanol
• (S)-1-(Isopropylamino)-3-(2-methoxyphenoxy)propan-2-ol
• 2-Propanol, 1-(2-methoxyphenoxy)-3-((1-methylethyl)amino)-, (S)-
• 2-Propanol, 1-(2-methoxyphenoxy)-3-[(1-methylethyl)amino]-, (2S)-
• Levomoprolol [INN]
• Levomoprololum
• Levomoprololum [Latin]
• Levotensin
• Moprolol l-form
• Unii-K4Non6Fson

(S)-1-(Isopropylamino)-3-(2-methoxyphenoxy)propan-2-ol

CAS: 77164-20-6

Formula: C₁₃H₂₁NO₃

Molecular weight: 239.3107

Ref: IN-DA00G75I

Levomoprolol Hydrochloride

Controlled Product

CAS: 77164-20-6

Formula: C₁₃H₂₁NO₃

Color and Shape: Neat

Molecular weight: 239.31

Ref: TR-L375870

Levomoprolol-d7

Controlled Product

CAS: 77164-20-6

Formula: C₁₃D₇H₁₄NO₃

Color and Shape: Neat

Molecular weight: 246.354

Ref: TR-L375872

Levomoprolol

CAS: 77164-20-6

Levomoprolol, (S)-enantiomer of the moprololis, is a beta adrenergic antagonist.

Formula: C₁₃H₂₁NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 239.31

Ref: TM-T25694