CAS 77175-51-0

Croconazole

Description:

Croconazole is an antifungal agent primarily used in the treatment of various fungal infections. It belongs to the class of imidazole derivatives, which are known for their ability to inhibit the synthesis of ergosterol, a critical component of fungal cell membranes. This mechanism disrupts the integrity of the fungal cell membrane, leading to cell death. Croconazole exhibits broad-spectrum antifungal activity, making it effective against a range of pathogenic fungi. The substance is typically administered topically or systemically, depending on the type and severity of the infection. In terms of physical properties, croconazole is characterized by its relatively low solubility in water, which can influence its formulation and delivery methods. Additionally, it may exhibit varying degrees of stability under different environmental conditions, such as light and temperature. Safety and efficacy profiles are essential considerations in its use, and potential side effects may include local irritation or allergic reactions. Overall, croconazole represents a valuable option in antifungal therapy, particularly in cases where other treatments may be less effective.

Formula: C₁₈H₁₅ClN₂O

InChI: InChI=1S/C18H15ClN2O/c1-14(21-10-9-20-13-21)17-7-2-3-8-18(17)22-12-15-5-4-6-16(19)11-15/h2-11,13H,1,12H2

InChI key: InChIKey=WHPAGCJNPTUGGD-UHFFFAOYSA-N

SMILES: C(=C)(C1=C(OCC2=CC(Cl)=CC=C2)C=CC=C1)N3C=CN=C3

Synonyms:

• 1-(1-(2-((3-Chlorobenzyl)oxy)phenyl)vinyl)-1H-imidazole
• 1-(1-(o-((m-Chlorobenzyl)oxy)phenyl)vinyl)imidazole
• 1-(1-{2-[(3-chlorobenzyl)oxy]phenyl}ethenyl)-1H-imidazole
• 1-[1-[2-[(3-Chlorophenyl)methoxy]phenyl]ethenyl]-1H-imidazole
• 1H-Imidazole, 1-(1-(2-((3-chlorophenyl)methoxy)phenyl)ethenyl)-
• Croconazol
• Croconazol [French,Spanish]
• Croconazole [INN]
• Croconazolum
• Croconazolum [Latin]
• Unii-446254H55G
• Viniconazole
• Croconazole

1H-Imidazole, 1-[1-[2-[(3-chlorophenyl)methoxy]phenyl]ethenyl]-

CAS: 77175-51-0

Formula: C₁₈H₁₅ClN₂O

Purity: 95%

Molecular weight: 310.7775

Ref: IN-DA00ICT3

Croconazole

CAS: 77175-51-0

Croconazole exhibited dose-dependent inhibitory activity on the 5-lipoxygenase (5-LOX) of neutrophils.

Formula: C₁₈H₁₅ClN₂O

Purity: 99.71%

Color and Shape: Solid

Molecular weight: 310.78

Ref: TM-T9878

Croconazole

CAS: 77175-51-0

Croconazole

Purity: ≥98%

Molecular weight: 310.78g/mol

Ref: 54-BUP12429

Croconazole

CAS: 77175-51-0

Formula: C₁₈H₁₅ClN₂O

Molecular weight: 310.78

Ref: 7W-GP2897

Cloconazole

Controlled Product

CAS: 77175-51-0

Formula: C₁₈H₁₅ClN₂O

Color and Shape: Neat

Molecular weight: 310.777

Ref: TR-C273940

Cloconazole-D6

Controlled Product

CAS: 77175-51-0

Formula: C₁₈D₆H₉ClN₂O

Color and Shape: Neat

Molecular weight: 316.815

Ref: TR-C273942