CAS 77181-69-2

Sorivudine

Description:

Sorivudine is an antiviral compound primarily used in the treatment of herpes simplex virus infections. It is classified as a nucleoside analog, specifically a pyrimidine derivative, which inhibits viral DNA synthesis by mimicking the natural nucleosides that are essential for viral replication. Sorivudine exhibits a high affinity for viral thymidine kinase, leading to the selective phosphorylation of the drug and subsequent incorporation into viral DNA, ultimately disrupting the replication process. The compound is known for its effectiveness against various strains of herpes viruses, including those resistant to other antiviral agents. In terms of physical properties, Sorivudine is typically a white to off-white crystalline powder, and it is soluble in water and organic solvents, which facilitates its formulation in pharmaceutical preparations. However, it is important to note that Sorivudine can have side effects and may interact with other medications, necessitating careful consideration in clinical use. Overall, its unique mechanism of action and antiviral properties make it a significant compound in the field of antiviral therapy.

Formula: C₁₁H₁₃BrN₂O₆

InChI: InChI=1/C11H13BrN2O6/c12-2-1-5-3-14(11(19)13-9(5)18)10-8(17)7(16)6(4-15)20-10/h1-3,6-8,10,15-17H,4H2,(H,13,18,19)/b2-1+/t6-,7-,8+,10-/m1/s1

InChI key: InChIKey=GCQYYIHYQMVWLT-HQNLTJAPSA-N

SMILES: O=C1N(C=C(/C=C/Br)C(=O)N1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O

Synonyms:

• (+)-1-beta-D-Arabinofuranosyl-5-((E)-2-bromovinyl)uracil
• (E)-1-beta-D-Arabinofuranosyl-5-(2-bromoethenyl)-2,4(1H,3H)-pyrimidinedione
• (E)-5-(2-Bromovinyl)-1-(β-<span class="text-smallcaps">D</span>-arabinofuranosyl)uracil
• (E)-5-(2-Bromovinyl)-1-beta-D-arabinofuranosyluracil
• (E)-5-(2-Bromovinyl)uridine
• 1-beta-D-Arabinofuranosyl-(E)-5-(2-bromovinyl)uracil
• 1-beta-D-arabinofuranosyl-5-[(E)-2-bromoethenyl]pyrimidine-2,4(1H,3H)-dione
• 1-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-(E)-5-(2-bromovinyl)uracil
• 1-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-5-(2-bromovinyl)uracil
• 1-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-5-[(1E)-2-bromoethenyl]-2,4(1H,3H)-pyrimidinedione
• 2,4(1H,3H)-Pyrimidinedione, 1-beta-D-arabinofuranosyl-5-(2-bromoethenyl)-, (E)-
• 2,4(1H,3H)-Pyrimidinedione, 1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-5-(2-bromoethenyl)-, (E)-
• 2,4(1H,3H)-Pyrimidinedione, 1-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-5-[(1E)-2-bromoethenyl]-
• 5-Bromovinyl-araU
• Arabinosyl (E)-5-(2-bromovinyl)uracil
• BV-Ara-U
• BVaraU
• Bravavir
• Bromovinyluridine
• Brovavir
• Ccris 5285
• Dru-0136
• Sorivudina
• Sorivudina [INN-Spanish]
• Sorivudine [USAN:INN:BAN:JAN]
• Sorivudinum
• Sorivudinum [INN-Latin]
• Sq-32756
• Usevir
• Yn-72
• 2,4(1H,3H)-Pyrimidinedione, 1-β-D-arabinofuranosyl-5-(2-bromoethenyl)-, (E)-
• 1-β-D-Arabinofuranosyl-(E)-5-(2-bromovinyl)uracil
• 1-β-D-Arabinofuranosyl-5-[(1E)-2-bromoethenyl]-2,4(1H,3H)-pyrimidinedione
• 2,4(1H,3H)-Pyrimidinedione, 1-β-D-arabinofuranosyl-5-[(1E)-2-bromoethenyl]-
• sorivudine
• BV-araU
• 1-β-D-Arabinofuranosyl-5-[(E)-2-bromovinyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
• Sorivudine (jan/usan/inn)
• 1-(β-D-Arabinofuranosyl)-5-[(E)-2-bromoethenyl]uracil
• D01734
• Sorivudin

1-β-D-Arabinofuranosyl-5-[(1E)-2-bromoethenyl]-2,4(1H,3H)-pyrimidinedione

CAS: 77181-69-2

Formula: C₁₁H₁₃BrN₂O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 349.1347

Ref: IN-DA003AJW

Sorivudine

CAS: 77181-69-2

Sorivudine

Purity: ≥95%

Molecular weight: 349.13g/mol

Ref: 54-BUP01729

Sorivudine

CAS: 77181-69-2

Formula: C₁₁H₁₃BrN₂O₆

Molecular weight: 349.14

Ref: 4Z-S-095001

SORIVUDINE

CAS: 77181-69-2

Purity: ≥97%

Molecular weight: 349.1369934

Ref: 10-F843954

Sorivudine

Controlled Product

CAS: 77181-69-2

Formula: C₁₁H₁₃BrN₂O₆

Color and Shape: Neat

Molecular weight: 349.135

Ref: TR-S677200

Sorivudine

CAS: 77181-69-2

Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.

Formula: C₁₁H₁₃BrN₂O₆

Purity: 99.74%

Color and Shape: Solid

Molecular weight: 349.13

Ref: TM-T16911