CAS 77191-36-7

Nefiracetam

Description:

Nefiracetam is a nootropic compound belonging to the racetam family, primarily known for its cognitive-enhancing properties. It is characterized by its ability to modulate neurotransmitter systems, particularly by influencing acetylcholine and glutamate receptors, which are crucial for learning and memory processes. Nefiracetam is often studied for its potential neuroprotective effects and its ability to improve cognitive function in various contexts, including age-related cognitive decline and certain neurological disorders. The substance is typically administered orally and is lipophilic, allowing it to cross the blood-brain barrier effectively. Its pharmacokinetics suggest a relatively rapid onset of action, with effects that may last several hours. While nefiroacetam is not approved for medical use in many countries, it has garnered interest in the research community for its potential therapeutic applications. As with any nootropic, the safety profile and long-term effects of nefiroacetam require further investigation to fully understand its efficacy and potential side effects.

Formula: C₁₄H₁₈N₂O₂

InChI: InChI=1/C14H18N2O2/c1-10-5-3-6-11(2)14(10)15-12(17)9-16-8-4-7-13(16)18/h3,5-6H,4,7-9H2,1-2H3,(H,15,17)

InChI key: InChIKey=NGHTXZCKLWZPGK-UHFFFAOYSA-N

SMILES: N(C(CN1C(=O)CCC1)=O)C2=C(C)C=CC=C2C

Synonyms:

• 1-Pyrrolidineacetamide, N-(2,6-dimethylphenyl)-2-oxo-
• 2-(2-Oxo-1-pyrrolidinyl)-N-(2,6-dimethylphenyl)acetamide
• Dm 9384
• Dmmpa
• Dmppa
• Dzl 221
• N-(2,6-Dimethylphenyl)-2-(2-oxo-1-pyrrolidinyl)acetamide
• N-(2,6-Dimethylphenyl)-2-Oxo-1-Pyrrolidineacetamide
• N-(2,6-dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide
• Translon
• [(2,6-Dimethylphenyl)Aminocarbonylmethyl]Chloride
• Nefiracetam
• DM-9384, (2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide)
• dm9384
• 2',6'-Dimethyl-2-(2-oxo-1-pyrrolidinyl)acetoanilide
• 2-oxo-1-pyrrolidinylaceticacid,2,6-dimethylanilide

Nefiracetam

CAS: 77191-36-7

Formula: C₁₄H₁₈N₂O₂

Purity: >98.0%(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 246.31

Ref: 3B-N0996

Nefiracetam

CAS: 77191-36-7

Formula: C₁₄H₁₈N₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 246.3049

Ref: IN-DA008NME

Nefiracetam

CAS: 77191-36-7

Nefiracetam (DM9384), in Phase 2 trials, enhances GABA, choline, monoamine systems, and treats Ro 5-4864 convulsions.

Formula: C₁₄H₁₈N₂O₂

Purity: 97.37%

Color and Shape: White To Off-White Crystalline Powder

Molecular weight: 246.3

Ref: TM-T0169

Nefiracetam

CAS: 77191-36-7

Nefiracetam

Purity: 98%

Molecular weight: 246.3g/mol

Ref: 54-OR1027525

Nefiracetam

CAS: 77191-36-7

Nefiracetam

Purity: ≥90%

Molecular weight: 246.3g/mol

Ref: 54-BUP16894

Nefiracetam

CAS: 77191-36-7

Formula: C₁₄H₁₈N₂O₂

Molecular weight: 246.30

Ref: 7W-GP3027

N-(2,6-Dimethylphenyl)-2-(2-oxopyrrolidin-1-yl)acetamide

CAS: 77191-36-7

Formula: C₁₄H₁₈N₂O₂

Purity: 97%

Molecular weight: 246.31

Ref: 10-F241232

Nefiracetam

Controlled Product

CAS: 77191-36-7

Applications Nefiracetam improves post-ischemia evoke-nonconvulsive seizure by altering pro-inflammatory cytokines.
References Fu, C. et al: Cell. Phys. Biochem., 37, 2023 (2015);

Formula: C₁₄H₁₈N₂O₂

Color and Shape: Neat

Molecular weight: 246.30

Ref: TR-N389395

Nefiracetam

CAS: 77191-36-7

Nefiracetam is a nootropic drug used for the treatment of Alzheimer's disease, Parkinson's disease, and other cognitive disorders. It binds to voltage-dependent calcium channels and inhibits neuronal death. Nefiracetam also has a protective effect on the brain from thermal expansion. This drug has been shown to be safe in human serum at doses up to 1,000 mg/kg and was not found to be toxic in animal toxicity studies. Nefiracetam is also effective in treating HIV infection by inhibiting cholinergic neurotransmission. It has been shown to increase locomotor activity and improve energy metabolism in the caudate putamen of rats with stroke-induced brain damage.

Formula: C₁₄H₁₈N₂O₂

Purity: Min. 95%

Molecular weight: 246.3 g/mol

Ref: 3D-CDA19136