CAS 77209-77-9

L-γ-Glutamyl-S-[(1R,2E,4E,6Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6-pentadecatrien-1-yl]-L-cysteinylglycine

Description:

L-γ-Glutamyl-S-[(1R,2E,4E,6Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6-pentadecatrien-1-yl]-L-cysteinylglycine, with the CAS number 77209-77-9, is a complex peptide derivative characterized by its unique structure that includes a γ-glutamyl group and a cysteinylglycine moiety. This compound features a long hydrocarbon chain with multiple double bonds, indicating it is a polyunsaturated fatty acid derivative. The presence of both carboxylic acid and hydroxyl functional groups suggests it may exhibit amphiphilic properties, which could influence its solubility and interaction with biological membranes. Its specific stereochemistry, indicated by the (R) and (S) designations, implies that it may have distinct biological activities or interactions, potentially making it relevant in biochemical pathways or therapeutic applications. Overall, this compound's intricate structure and functional groups contribute to its potential roles in biological systems, although further research would be necessary to elucidate its specific functions and applications.

Formula: C₃₀H₄₉N₃O₉S

InChI: InChI=1/C30H49N3O9S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(34)15-14-17-27(36)37)43-21-23(29(40)32-20-28(38)39)33-26(35)19-18-22(31)30(41)42/h9-13,16,22-25,34H,2-8,14-15,17-21,31H2,1H3,(H,32,40)(H,33,35)(H,36,37)(H,38,39)(H,41,42)/b10-9+,12-11+,16-13+/t22-,23-,24-,25?/m0/s1

InChI key: InChIKey=AIJDQMYBRDJHHT-ABAXQOPJSA-N

SMILES: [C@@H](CS[C@@H]([C@H](CCCC(O)=O)O)/C=C/C=C/C=C\CCCCCCCC)(NC(CC[C@@H](C(O)=O)N)=O)C(NCC(O)=O)=O

Synonyms:

• Leukotriene C3
• L-γ-Glutamyl-S-[(1R,2E,4E,6Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6-pentadecatrien-1-yl]-L-cysteinylglycine
• Glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6-pentadecatrienyl]-L-cysteinyl-
• Glycine, N-[S-[1-(4-carboxy-1-hydroxybutyl)-2,4,6-pentadecatrienyl]-N-L-γ-glutamyl-L-cysteinyl]-, [R-[R*,S*-(E,E,Z)]]-
• Glycine, L-γ-glutamyl-S-[(1R,2E,4E,6Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6-pentadecatrien-1-yl]-L-cysteinyl-