CAS 7722-44-3

(6R)-N-[(2S)-4-amino-1-{[(2S,3R)-1-{[(2S)-4-amino-1-oxo-1-{[(3S,6R,9S,12S,15R,18S,21S)-6,9,18-tris(2-aminoethyl)-3-[(1R)-1-hydroxyethyl]-12,15-bis(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]amino}butan-2-yl]am

Description:

The chemical substance with the name provided is a complex organic molecule, characterized by its intricate structure that includes multiple functional groups and stereocenters. It features a heptaazacyclotricosane backbone, which is a cyclic compound containing nitrogen atoms, contributing to its potential biological activity. The presence of amino groups suggests that it may participate in various biochemical interactions, possibly acting as a ligand or a precursor in synthetic pathways. The molecule also contains multiple oxo groups, indicating potential reactivity and the ability to form coordination complexes. Its stereochemistry, denoted by the (R) and (S) configurations, implies that it may exhibit specific spatial arrangements that can influence its biological activity and interactions with other molecules. The CAS number 7722-44-3 corresponds to hydrogen peroxide, a simple yet powerful oxidizing agent, which is widely used in various applications, including disinfection, bleaching, and as an oxidizer in chemical reactions. Overall, the substance's complexity and functional diversity suggest potential applications in pharmaceuticals, materials science, and biochemistry.

Formula: C₅₃H₁₀₀N₁₆O₁₃

InChI: InChI=1/C53H100N16O13/c1-9-30(6)12-10-11-13-41(72)60-33(14-20-54)48(77)69-43(32(8)71)53(82)65-36(17-23-57)45(74)64-38-19-25-59-52(81)42(31(7)70)68-49(78)37(18-24-58)62-44(73)34(15-21-55)63-50(79)39(26-28(2)3)67-51(80)40(27-29(4)5)66-46(75)35(16-22-56)61-47(38)76/h28-40,42-43,70-71H,9-27,54-58H2,1-8H3,(H,59,81)(H,60,72)(H,61,76)(H,62,73)(H,63,79)(H,64,74)(H,65,82)(H,66,75)(H,67,80)(H,68,78)(H,69,77)/t30-,31-,32-,33+,34+,35+,36+,37-,38+,39+,40-,42+,43+/m1/s1

Colistin A

CAS: 7722-44-3

Colistin A, from Paenibacillus polymyxa, is an antibiotic effective against Gram-negative bacilli, part of the polymyxin class.

Formula: C₅₃H₁₀₀N₁₆O₁₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 1169.46

Ref: TM-T25269

Colistin A Pentatrifluoroacetate (Polymyxin E1 Pentatrifluoroacetate)

CAS: 1264-72-8, 7722-44-3

Formula: C₅₃H₁₀₀N₁₆O₁₃·5C₂HF₃O₂

Molecular weight: 1169.48 5*114.02

Ref: 4Z-PC-321002

Colistin A Sulfate Hydrate (~90%)

CAS: 7722-44-3

Applications Colistin A Sulfate Hydrate is used as an antibiotic in the treatment of infectious diseases resulting from multi-drug resistant (MDR) gram-negative bacteria.
References Wallace, S. et al.: J. Pharm. Sci., 102, 1578 (2013); Suzuki, T., et al.: J. Biochem., 54, 25 (1963); Barnett, M., et al.: Br. J. Pharmacol. Chemother., 23, 552 (1964); Littlewood, J, M., et al.: Respir. Med., 94, 632 (2000); Li, J., et al.: Int. J. Antimicrob. Ag., 25, 11 (2005); Tsubery, H. et al.: Antimicrob. Agents Chemother., 49, 3122 (2005)

Formula: C₅₃H₁₀₀O₁₃N₁₆·xH₂SO₄·xH₂O

Purity: ~90%

Color and Shape: White To Beige

Molecular weight: 1169.46

Ref: TR-C641510

Colistin A

CAS: 7722-44-3

Colistin A is an antimicrobial peptide, which is a type of polymyxin antibiotic derived from the bacterium *Paenibacillus polymyxa*. It exerts its bactericidal effect by interacting electrostatically with the lipopolysaccharides and phospholipids in the outer membrane of Gram-negative bacteria. This action disrupts the bacterial cell membrane, leading to increased permeability and cell death.

Formula: C₅₃H₁₀₀N₁₆O₁₃

Purity: Min. 95%

Molecular weight: 1,169.5 g/mol

Ref: 3D-HAA72244

Colistin A

CAS: 7722-44-3

Formula: C₅₃H₁₀₀N₁₆O₁₃

Molecular weight: 1169.5

Ref: ST-EA-CP-C116013