CAS 77229-68-6

4-[(6-methoxyquinolin-8-yl)amino]pentanoic acid

Description:

4-[(6-Methoxyquinolin-8-yl)amino]pentanoic acid, with the CAS number 77229-68-6, is a chemical compound characterized by its unique structure that includes a quinoline moiety and an amino acid component. This compound features a pentanoic acid backbone, which contributes to its potential as a bioactive molecule. The presence of the methoxy group on the quinoline ring enhances its solubility and may influence its biological activity. The amino group allows for potential interactions with biological targets, making it of interest in medicinal chemistry. This compound may exhibit properties such as antimicrobial, anti-inflammatory, or anticancer activities, although specific biological effects would depend on further empirical studies. Its molecular structure suggests it could participate in hydrogen bonding and other interactions, which are crucial for its reactivity and functionality in various chemical environments. As with many compounds containing heterocyclic rings, it may also display unique spectral characteristics useful for identification and analysis in research settings.

Formula: C₁₅H₁₈N₂O₃

InChI: InChI=1/C15H18N2O3/c1-10(5-6-14(18)19)17-13-9-12(20-2)8-11-4-3-7-16-15(11)13/h3-4,7-10,17H,5-6H2,1-2H3,(H,18,19)

SMILES: CC(CCC(=O)O)Nc1cc(cc2cccnc12)OC

Synonyms:

• 8-(3-Carboxy-1-Methylpropylamino)-6-Methoxyquinoline
• Carboxyprimaquine

Carboxy Primaquine

CAS: 77229-68-6

Formula: C₁₅H₁₈N₂O₃

Color and Shape: Solid

Molecular weight: 274.3150

Ref: IN-DA005OMZ

Carboxyprimaquine

CAS: 77229-68-6

Formula: C₁₅H₁₈N₂O₃

Molecular weight: 274.32

Ref: 4Z-P-296006

Carboxyprimaquine-13C-d3

CAS: 77229-68-6

Formula: C₁₄₁₃CH₁₅D₃N₂O₃

Molecular weight: 278.33

Ref: 4Z-P-296007

Carboxy Primaquine-d4 (Major)

Controlled Product

CAS: 77229-68-6

Formula: C₁₅H₁₄D₄N₂O₃

Color and Shape: Neat

Molecular weight: 278.34

Ref: TR-C181262

Carboxy Primaquine

Controlled Product

CAS: 77229-68-6

Applications Carboxy Primaquine, is a derivative of Primaquine (P733500), an Antimalarial agent.
References Marrs, T., et al.: Toxicol Lett., 36, 281 (1987), Karbwang, J., et al.: Clin. Pharmacokinetic., 27, 104 (1994), Noedl, H., et al.: Antimicrob. Agents Chemother., 45, 2106 (2010)

Formula: C₁₅H₁₈N₂O₃

Color and Shape: Neat

Molecular weight: 274.32

Ref: TR-C181260

Carboxy Primaquine

CAS: 77229-68-6

Carboxy Primaquine is an antimicrobial agent that inhibits the activity of cytochrome P450 enzymes. It is used to treat malaria, as it has potent anti-malarial activity against Plasmodium falciparum and Plasmodium vivax. Carboxy Primaquine is also used to treat other protozoal and bacterial infections, such as toxoplasmosis, pneumocystosis, leishmaniasis, trypanosomiasis, and leptospirosis. This drug has been shown to have immunogenic properties in vivo in humans. Inhibition of carboxyprimaquine metabolism by glucuronide conjugates has been demonstrated in liver cells from humans and rats. The pharmacokinetic profile of this drug includes a rapid absorption from the gastrointestinal tract, followed by a terminal elimination phase with a half-life of approximately 2 hours. Carboxy Primaquine is not carcinogenic in animal models

Formula: C₁₅H₁₈N₂O₃

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 274.32 g/mol

Ref: 3D-CDA22968