CymitQuimica logo

CAS 77259-54-2

:

dynorphin A fragment 1-9

Description:
Dynorphin A fragment 1-9, with the CAS number 77259-54-2, is a peptide that is derived from the larger dynorphin A molecule, which is an endogenous opioid peptide. This fragment consists of the first nine amino acids of the dynorphin A sequence and is known for its role in modulating pain, stress, and emotional responses through its interaction with opioid receptors, particularly the kappa-opioid receptor. The peptide exhibits characteristics typical of opioid peptides, including the ability to bind to specific receptors in the central nervous system, leading to analgesic effects. It is generally hydrophilic due to its amino acid composition, which influences its solubility and biological activity. Additionally, dynorphin A fragment 1-9 is involved in various physiological processes, including the regulation of mood and the modulation of neuroendocrine functions. Its study is significant in understanding pain mechanisms and developing potential therapeutic applications in pain management and psychiatric disorders.
Formula:C52H84N18O11
InChI:InChI=1/C52H84N18O11/c1-5-30(4)42(48(79)68-37(49(80)81)16-11-23-62-52(58)59)70-45(76)36(15-10-22-61-51(56)57)66-44(75)35(14-9-21-60-50(54)55)67-46(77)38(24-29(2)3)69-47(78)39(26-31-12-7-6-8-13-31)65-41(73)28-63-40(72)27-64-43(74)34(53)25-32-17-19-33(71)20-18-32/h6-8,12-13,17-20,29-30,34-39,42,71H,5,9-11,14-16,21-28,53H2,1-4H3,(H,63,72)(H,64,74)(H,65,73)(H,66,75)(H,67,77)(H,68,79)(H,69,78)(H,70,76)(H,80,81)(H4,54,55,60)(H4,56,57,61)(H4,58,59,62)/t30-,34-,35-,36-,37-,38-,39-,42-/m0/s1
SMILES:CC[C@H](C)[C@@H](C(=N[C@@H](CCCNC(=N)N)C(=O)O)O)N=C([C@H](CCCNC(=N)N)N=C([C@H](CCCNC(=N)N)N=C([C@H](CC(C)C)N=C([C@H](Cc1ccccc1)N=C(CN=C(CN=C([C@H](Cc1ccc(cc1)O)N)O)O)O)O)O)O)O
Synonyms:
  • Dynorphin A (1-9)
  • H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-OH
  • L-tyrosylglycylglycyl-L-phenylalanyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-N~5~-(diaminomethylidene)-L-ornithyl-L-isoleucyl-N~5~-(diaminomethylidene)-L-ornithine
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 1 products.
  • Dynorphin A (1-9)
    Biosynth
    + Info

    Dynorphin A (1-9)

    CAS:

    Dynorphin A (1-9) H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-OH is a substrate binding inhibitor that blocks potassium channels. Dynorphin A (1-9) H-Tyr-Gly-Gly-Phe-Leu Arg Arg Ile Arg OH binds to the d -alanine site of the potassium channel and inhibits glutamate release from presynaptic terminals. Dynorphin A (1 9) H Tyr Gly Gly Phe Leu Arg Arg Ile Arg OH has been shown to be a potent inhibitor of aminopeptidase activity in vitro, which may be due to its affinity for the substrate binding site on the enzyme. Its inhibition of aminopeptidase activity may lead to an increase in opioid peptides such as dynorphins and enkephalins. Dynorphin A (1 9) H Tyr Gly Gly Phe

    Formula:C52H84N18O11
    Purity:Min. 95%
    Molecular weight:1,137.34 g/mol

    Ref: 3D-FD108729

    5mg
    869.00€
    10mg
    1,045.00€
    25mg
    2,085.00€