CAS 77275-70-8

Substance P,2-D-proline-7-D-phenylalanine-9-D-tryptophan-

Description:

Substance P,2-D-proline-7-D-phenylalanine-9-D-tryptophan, identified by its CAS number 77275-70-8, is a synthetic peptide that is a derivative of the neuropeptide Substance P. This compound is characterized by its unique amino acid sequence, which includes D-proline, D-phenylalanine, and D-tryptophan, contributing to its structural stability and resistance to enzymatic degradation. It is known for its potential role in modulating pain perception and inflammatory responses, as well as its involvement in various physiological processes. The presence of D-amino acids in its structure enhances its bioactivity and pharmacological properties. This peptide is often studied in the context of neurobiology and pharmacology, particularly for its interactions with neurokinin receptors. Its synthesis and characterization involve advanced techniques in peptide chemistry, and it may have applications in drug development and therapeutic interventions targeting pain and neurogenic inflammation.

Formula: C₇₂H₁₀₅N₁₉O₁₃S

Synonyms:

• (D-Pro2,D-Phe7,D-Trp9)-substanceP 1-11
• D-Pro2-D-Phe7-D-Trp9-substance P
• 15: PN: US20020037833 SEQID: 14 unclaimed sequence
• ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2
• Substance P, 2-D-proline-7-D-phenylalanine-9-D-tryptophan-
• substance P, Pro(2)-Phe(7)-Trp(9)-
• H-ARG-D-PRO-LYS-PRO-GLN-GLN-D-PHE-PHE-D-TRP-LEU-MET-NH2
• (D-PROLINE2,D-PHENYLALANINE7,D-TRYPTOPHAN9)SUBSTANCE P)
• Substance P, (D-Pro2, D-Phe7, D-Trp9)