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CAS 7728-40-7

:

Monoethylglycinexylidide

Description:
Monoethylglycinexylidide, with the CAS number 7728-40-7, is a chemical compound primarily recognized for its application in the field of pharmaceuticals, particularly as a local anesthetic. It is a derivative of lidocaine and is characterized by its ability to block sodium channels, thereby inhibiting nerve impulse transmission. This compound typically appears as a white to off-white crystalline powder and is soluble in water and organic solvents, which enhances its utility in various formulations. Its pharmacological properties include rapid onset and moderate duration of action, making it effective for local anesthesia in medical procedures. Additionally, it is important to handle this substance with care, as it can exhibit toxicity at high concentrations. Safety data sheets should be consulted for information on handling, storage, and potential hazards. Overall, Monoethylglycinexylidide is a significant compound in anesthetic practices, contributing to pain management in clinical settings.
Formula:C12H18N2O
InChI:InChI=1S/C12H18N2O/c1-4-13-8-11(15)14-12-9(2)6-5-7-10(12)3/h5-7,13H,4,8H2,1-3H3,(H,14,15)
InChI key:InChIKey=WRMRXPASUROZGT-UHFFFAOYSA-N
SMILES:N(C(CNCC)=O)C1=C(C)C=CC=C1C
Synonyms:
  • 2-(Ethylamino)-2′,6′-acetoxylidide
  • 2′,6′-Acetoxylidide, 2-(ethylamino)-
  • Monoethylglycinexylidide
  • Monoethylglycylxylidide
  • N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide
  • N-(N-Ethylglycyl)-2,6-xylidine
  • N-Ethylglycinexylidide
  • N1-(2,6-dimethylphenyl)-2-(ethylamino)acetamide
  • Norlidocaine
  • acetamide, N-(2,6-dimethylphenyl)-2-(ethylamino)-
  • See more synonyms
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Found 7 products.
  • MEGX

    CAS:
    Formula:C12H18N2O
    Molecular weight:206.28

    Ref: 7W-GL9214

    ne
    To inquire
  • Monoethylglycinexylidide

    CAS:
    <p>Monoethylglycinexylidide</p>
    Purity:95%
    Molecular weight:206.29g/mol

    Ref: 54-OR1054387

    10g
    686.00€
  • Lidocaine EP Impurity D

    CAS:
    Formula:C12H18N2O
    Color and Shape:White To Off-White Solid
    Molecular weight:206.29

    Ref: 4Z-L-0627

    5mg
    To inquire
    10mg
    444.00€
    25mg
    635.00€
    50mg
    825.00€
    100mg
    To inquire
  • Norlidocaine

    CAS:
    Formula:C12H18N2O
    Color and Shape:Off-White
    Molecular weight:206.2841

    Ref: 04-C15651550

    10mg
    221.00€
  • Lidocaine EP Impurity D

    CAS:
    Formula:C12H18N2O
    Molecular weight:206.28

    Ref: ST-EA-CP-L20004

    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Monoethylglycinexylidide

    CAS:
    Purity:98%
    Molecular weight:206.2890015

    Ref: 10-F614794

    1g
    362.00€
  • Monoethylglycinexylidine

    CAS:
    <p>Monoethylglycinexylidine (MEGX) is a drug that has been shown to be effective in the treatment of chronic viral hepatitis. It has an activity index of 0.6-2.0 and can be used as a diagnostic tool for hepatic impairment. MEGX has also been found to be more effective in patients with primary sclerosing cholangitis than in those with non-primary sclerosing cholangitis. MEGX inhibits the P450 enzyme, which is involved in the metabolism of xenobiotics and endogenous compounds, and also inhibits Lidocaine-induced bronchoconstriction. The structural analysis of MEGX showed that it forms a stable complex with the active site of P450 enzymes, but does not form stable complexes with other enzymes such as cytochrome P450 reductase or epoxide hydrolase. In vivo experiments have shown that MEGX inhibits liver regeneration in mice by inhibiting hepatocyte</p>
    Formula:C12H18N2O
    Purity:Min. 95%
    Molecular weight:206.28 g/mol

    Ref: 3D-HAA72840

    2500mg
    478.00€